Proper Read Filtering Method to Adequately Analyze Whole-Transcriptome Sequencing and RNA Based Immune Repertoire Sequencing Data for Tumor Milieu Research

Proper Read Filtering Method to Adequately Analyze Whole-Transcriptome Sequencing and RNA Based Immune Repertoire Sequencing Data for Tumor Milieu Research

Analysis of the T-cell receptor (TCR) repertoire is essential to characterize the extensive collections of T-cell populations with recognizing antigens in cancer research, and whole transcriptome sequencing (WTS) and immune repertoire sequencing (IR-seq) are commonly used for this measure. To date,...

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Bibliographic Details
Main Authors: Sungyoung Lee, Seulki Song, Sung-Soo Yoon, Youngil Koh, Hongseok Yun
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
T-cell receptor
immune repertoire
immune repertoire sequencing
whole transcriptome sequencing
clonotype
Online Access:https://www.mdpi.com/2072-6694/12/12/3693

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