Countercurrents: DCIS or Cancer? Why All the Confusion?

At present, women with ductal carcinoma in situ are counseled that they have a pre-malignant condition which carries the possibility of progression to a fully malignant breast cancer. However, in most cases, the treatment of DCIS resembles that of a small invasive breast cancer and this is a source...

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Main Authors: Steven A. Narod, Victoria Sopik
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/29/7/392
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author Steven A. Narod
Victoria Sopik
author_facet Steven A. Narod
Victoria Sopik
author_sort Steven A. Narod
collection DOAJ
description At present, women with ductal carcinoma in situ are counseled that they have a pre-malignant condition which carries the possibility of progression to a fully malignant breast cancer. However, in most cases, the treatment of DCIS resembles that of a small invasive breast cancer and this is a source of confusion to many. In order to properly evaluate the benefit of radiotherapy, mastectomy and contralateral mastectomy, it is necessary to consider the risks of ipsilateral invasive cancer and of contralateral breast cancer in women with DCIS and with small invasive breast cancer. Several registry-based studies indicate that the risks of ipsilateral and contralateral cancer are similar in the two conditions and therefore a similar approach to treatment is rational.
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spelling doaj.art-c3d4720274a34037a164a1674595a85f2023-12-01T22:02:55ZengMDPI AGCurrent Oncology1198-00521718-77292022-07-012974936494010.3390/curroncol29070392Countercurrents: DCIS or Cancer? Why All the Confusion?Steven A. Narod0Victoria Sopik1Women’s College Research Institute, Women’s College Hospital, Toronto, ON M5S 1B2, CanadaWomen’s College Research Institute, Women’s College Hospital, Toronto, ON M5S 1B2, CanadaAt present, women with ductal carcinoma in situ are counseled that they have a pre-malignant condition which carries the possibility of progression to a fully malignant breast cancer. However, in most cases, the treatment of DCIS resembles that of a small invasive breast cancer and this is a source of confusion to many. In order to properly evaluate the benefit of radiotherapy, mastectomy and contralateral mastectomy, it is necessary to consider the risks of ipsilateral invasive cancer and of contralateral breast cancer in women with DCIS and with small invasive breast cancer. Several registry-based studies indicate that the risks of ipsilateral and contralateral cancer are similar in the two conditions and therefore a similar approach to treatment is rational.https://www.mdpi.com/1718-7729/29/7/392DCISbreast cancermalignancy
spellingShingle Steven A. Narod
Victoria Sopik
Countercurrents: DCIS or Cancer? Why All the Confusion?
Current Oncology
DCIS
breast cancer
malignancy
title Countercurrents: DCIS or Cancer? Why All the Confusion?
title_full Countercurrents: DCIS or Cancer? Why All the Confusion?
title_fullStr Countercurrents: DCIS or Cancer? Why All the Confusion?
title_full_unstemmed Countercurrents: DCIS or Cancer? Why All the Confusion?
title_short Countercurrents: DCIS or Cancer? Why All the Confusion?
title_sort countercurrents dcis or cancer why all the confusion
topic DCIS
breast cancer
malignancy
url https://www.mdpi.com/1718-7729/29/7/392
work_keys_str_mv AT stevenanarod countercurrentsdcisorcancerwhyalltheconfusion
AT victoriasopik countercurrentsdcisorcancerwhyalltheconfusion