Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica
Abstract Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained four new spirostanol glycosides, named ypsilandrosides U-X (1–4), and one new cholestanol glycoside, named ypsilandroside Y (5). Their structures have been established by extensive spectroscopic data and chem...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-05-01
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| Series: | Natural Products and Bioprospecting |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s13659-022-00337-0 |
| _version_ | 1818191911613104128 |
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| author | Wen-Tao Gao Ling-Ling Yu Jing Xie Long-Gao Xiao Shi-Juan Zhang Wen-Yi Ma Huan Yan Hai-Yang Liu |
| author_facet | Wen-Tao Gao Ling-Ling Yu Jing Xie Long-Gao Xiao Shi-Juan Zhang Wen-Yi Ma Huan Yan Hai-Yang Liu |
| author_sort | Wen-Tao Gao |
| collection | DOAJ |
| description | Abstract Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained four new spirostanol glycosides, named ypsilandrosides U-X (1–4), and one new cholestanol glycoside, named ypsilandroside Y (5). Their structures have been established by extensive spectroscopic data and chemical methods. Among them, compound 4 is a rare spirostanol glycoside which possesses a novel 5(6 → 7) abeo-steroidal aglycone, while compound 1 is a first spirostanol bisdesmoside attached to C-3 and C-12, respectively, isolated from the genus Ypsilandra. The induced platelet aggregation activity of the isolates was tested. Graphical Abstract |
| first_indexed | 2024-12-12T00:22:08Z |
| format | Article |
| id | doaj.art-c3d5257687bf435dae19c33e8a53d44f |
| institution | Directory Open Access Journal |
| issn | 2192-2195 2192-2209 |
| language | English |
| last_indexed | 2024-12-12T00:22:08Z |
| publishDate | 2022-05-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Natural Products and Bioprospecting |
| spelling | doaj.art-c3d5257687bf435dae19c33e8a53d44f2022-12-22T00:44:43ZengSpringerOpenNatural Products and Bioprospecting2192-21952192-22092022-05-011211910.1007/s13659-022-00337-0Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibeticaWen-Tao Gao0Ling-Ling Yu1Jing Xie2Long-Gao Xiao3Shi-Juan Zhang4Wen-Yi Ma5Huan Yan6Hai-Yang Liu7College of Traditional Chinese Medicine, Yunnan University of Chinese MedicineState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of SciencesAbstract Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained four new spirostanol glycosides, named ypsilandrosides U-X (1–4), and one new cholestanol glycoside, named ypsilandroside Y (5). Their structures have been established by extensive spectroscopic data and chemical methods. Among them, compound 4 is a rare spirostanol glycoside which possesses a novel 5(6 → 7) abeo-steroidal aglycone, while compound 1 is a first spirostanol bisdesmoside attached to C-3 and C-12, respectively, isolated from the genus Ypsilandra. The induced platelet aggregation activity of the isolates was tested. Graphical Abstracthttps://doi.org/10.1007/s13659-022-00337-0Ypsilandra thibeticaMelanthiaceaeYpsilandrosides U-YSpirostanol saponinsCholestanol saponins |
| spellingShingle | Wen-Tao Gao Ling-Ling Yu Jing Xie Long-Gao Xiao Shi-Juan Zhang Wen-Yi Ma Huan Yan Hai-Yang Liu Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica Natural Products and Bioprospecting Ypsilandra thibetica Melanthiaceae Ypsilandrosides U-Y Spirostanol saponins Cholestanol saponins |
| title | Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica |
| title_full | Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica |
| title_fullStr | Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica |
| title_full_unstemmed | Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica |
| title_short | Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica |
| title_sort | ypsilandrosides u y five new steroidal saponins from ypsilandra thibetica |
| topic | Ypsilandra thibetica Melanthiaceae Ypsilandrosides U-Y Spirostanol saponins Cholestanol saponins |
| url | https://doi.org/10.1007/s13659-022-00337-0 |
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