Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.
We investigated the association between oral hygiene indicators of periodontitis, tooth loss, and tooth brushing on the longitudinal fasting glucose level in non-diabetic subjects. Using a nationwide health screening database in Korea, we included non-diabetic individuals who received a health scree...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0253769 |
| _version_ | 1829477955419504640 |
|---|---|
| author | Tae-Jin Song Yoonkyung Chang Jimin Jeon Jinkwon Kim |
| author_facet | Tae-Jin Song Yoonkyung Chang Jimin Jeon Jinkwon Kim |
| author_sort | Tae-Jin Song |
| collection | DOAJ |
| description | We investigated the association between oral hygiene indicators of periodontitis, tooth loss, and tooth brushing on the longitudinal fasting glucose level in non-diabetic subjects. Using a nationwide health screening database in Korea, we included non-diabetic individuals who received a health screening program with oral health check in 2009-2010. We constructed a linear mixed model for the longitudinal data of fasting glucose from the baseline to 2015. During the 4.84-year of median follow-up, 91,963 individuals (mean age 56.2 at baseline) underwent 392,780 health examinations with fasting glucose level (mmol/L). The presence of periodontitis was 39.3%. In the multivariate linear mixed analysis, periodontitis was related with increased fasting glucose levels (β = 0.0084, standard error = 0.0035, p = 0.018). Similarly, tooth loss was associated with increased level of fasting glucose (β = 0.0246, standard error = 0.0038, p < 0.001). Compared with tooth brushing ≤2 times/day, tooth brushing ≥3 times/day was associated with decreased fasting glucose levels (β = -0.0207, standard error = 0.0033, p < 0.001). Our data showed that periodontitis and tooth loss were associated with increased fasting glucose levels in non-diabetic individuals. The study findings imply that frequent tooth brushing may reduce fasting glucose levels. Further research is needed to determine the effect of periodontal intervention on glycemic control. |
| first_indexed | 2024-12-14T17:05:31Z |
| format | Article |
| id | doaj.art-c3d6eb9cd1bd40e78e9f78c7ed7adf34 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T17:05:31Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c3d6eb9cd1bd40e78e9f78c7ed7adf342022-12-21T22:53:44ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01166e025376910.1371/journal.pone.0253769Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study.Tae-Jin SongYoonkyung ChangJimin JeonJinkwon KimWe investigated the association between oral hygiene indicators of periodontitis, tooth loss, and tooth brushing on the longitudinal fasting glucose level in non-diabetic subjects. Using a nationwide health screening database in Korea, we included non-diabetic individuals who received a health screening program with oral health check in 2009-2010. We constructed a linear mixed model for the longitudinal data of fasting glucose from the baseline to 2015. During the 4.84-year of median follow-up, 91,963 individuals (mean age 56.2 at baseline) underwent 392,780 health examinations with fasting glucose level (mmol/L). The presence of periodontitis was 39.3%. In the multivariate linear mixed analysis, periodontitis was related with increased fasting glucose levels (β = 0.0084, standard error = 0.0035, p = 0.018). Similarly, tooth loss was associated with increased level of fasting glucose (β = 0.0246, standard error = 0.0038, p < 0.001). Compared with tooth brushing ≤2 times/day, tooth brushing ≥3 times/day was associated with decreased fasting glucose levels (β = -0.0207, standard error = 0.0033, p < 0.001). Our data showed that periodontitis and tooth loss were associated with increased fasting glucose levels in non-diabetic individuals. The study findings imply that frequent tooth brushing may reduce fasting glucose levels. Further research is needed to determine the effect of periodontal intervention on glycemic control.https://doi.org/10.1371/journal.pone.0253769 |
| spellingShingle | Tae-Jin Song Yoonkyung Chang Jimin Jeon Jinkwon Kim Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study. PLoS ONE |
| title | Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study. |
| title_full | Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study. |
| title_fullStr | Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study. |
| title_full_unstemmed | Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study. |
| title_short | Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study. |
| title_sort | oral health and longitudinal changes in fasting glucose levels a nationwide cohort study |
| url | https://doi.org/10.1371/journal.pone.0253769 |
| work_keys_str_mv | AT taejinsong oralhealthandlongitudinalchangesinfastingglucoselevelsanationwidecohortstudy AT yoonkyungchang oralhealthandlongitudinalchangesinfastingglucoselevelsanationwidecohortstudy AT jiminjeon oralhealthandlongitudinalchangesinfastingglucoselevelsanationwidecohortstudy AT jinkwonkim oralhealthandlongitudinalchangesinfastingglucoselevelsanationwidecohortstudy |