Cigarette, cigar and pipe smoking, passive smoke exposure, and risk of pancreatic cancer: a population-based study in the San Francisco Bay Area
<p>Abstract</p> <p>Background</p> <p>To examine the influence of cigarette, cigar and pipe smoking, cessation of cigarette smoking and passive smoke exposure on the risk of pancreatic cancer.</p> <p>Methods</p> <p>Exposure data were collected dur...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-04-01
|
| Series: | BMC Cancer |
| Online Access: | http://www.biomedcentral.com/1471-2407/11/138 |
| _version_ | 1819026169679314944 |
|---|---|
| author | Wang Furong Holly Elizabeth A Tranah Gregory J Bracci Paige M |
| author_facet | Wang Furong Holly Elizabeth A Tranah Gregory J Bracci Paige M |
| author_sort | Wang Furong |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>To examine the influence of cigarette, cigar and pipe smoking, cessation of cigarette smoking and passive smoke exposure on the risk of pancreatic cancer.</p> <p>Methods</p> <p>Exposure data were collected during in-person interviews in a population-based case-control study of pancreatic cancer (N = 532 cases, N = 1701 controls) in the San Francisco Bay Area. Odds ratios (ORs) were adjusted for potential confounders.</p> <p>Results</p> <p>The adjusted odds ratio (OR) of pancreatic cancer among current smokers was 1.9 (95% confidence interval (CI), 1.4-2.7). A significant, positive trend in risk with increasing pack-years of smoking was observed (P-trend <0.0001). Compared with participants who continued to smoke, former smokers had no statistically significant elevation in risk of pancreatic cancer 10 years after smoking cessation, with risk reduced to that of never smokers regardless of prior smoking intensity. Both men and women experienced similar increased risk of pancreatic cancer with increasing smoking duration. Cigar and pipe smoking and exposure to passive smoke were not associated with pancreatic cancer.</p> <p>Conclusions</p> <p>Cigarette smoking is associated with an increased risk of pancreatic cancer. Smokers who had quit for ≥10 years no longer experienced an increased risk. Future work will help to determine the effect of declining smoking rates on pancreatic cancer incidence.</p> |
| first_indexed | 2024-12-21T05:22:18Z |
| format | Article |
| id | doaj.art-c3d7ab791a994ff3ba152fc6a39a6e32 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-21T05:22:18Z |
| publishDate | 2011-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-c3d7ab791a994ff3ba152fc6a39a6e322022-12-21T19:14:47ZengBMCBMC Cancer1471-24072011-04-0111113810.1186/1471-2407-11-138Cigarette, cigar and pipe smoking, passive smoke exposure, and risk of pancreatic cancer: a population-based study in the San Francisco Bay AreaWang FurongHolly Elizabeth ATranah Gregory JBracci Paige M<p>Abstract</p> <p>Background</p> <p>To examine the influence of cigarette, cigar and pipe smoking, cessation of cigarette smoking and passive smoke exposure on the risk of pancreatic cancer.</p> <p>Methods</p> <p>Exposure data were collected during in-person interviews in a population-based case-control study of pancreatic cancer (N = 532 cases, N = 1701 controls) in the San Francisco Bay Area. Odds ratios (ORs) were adjusted for potential confounders.</p> <p>Results</p> <p>The adjusted odds ratio (OR) of pancreatic cancer among current smokers was 1.9 (95% confidence interval (CI), 1.4-2.7). A significant, positive trend in risk with increasing pack-years of smoking was observed (P-trend <0.0001). Compared with participants who continued to smoke, former smokers had no statistically significant elevation in risk of pancreatic cancer 10 years after smoking cessation, with risk reduced to that of never smokers regardless of prior smoking intensity. Both men and women experienced similar increased risk of pancreatic cancer with increasing smoking duration. Cigar and pipe smoking and exposure to passive smoke were not associated with pancreatic cancer.</p> <p>Conclusions</p> <p>Cigarette smoking is associated with an increased risk of pancreatic cancer. Smokers who had quit for ≥10 years no longer experienced an increased risk. Future work will help to determine the effect of declining smoking rates on pancreatic cancer incidence.</p>http://www.biomedcentral.com/1471-2407/11/138 |
| spellingShingle | Wang Furong Holly Elizabeth A Tranah Gregory J Bracci Paige M Cigarette, cigar and pipe smoking, passive smoke exposure, and risk of pancreatic cancer: a population-based study in the San Francisco Bay Area BMC Cancer |
| title | Cigarette, cigar and pipe smoking, passive smoke exposure, and risk of pancreatic cancer: a population-based study in the San Francisco Bay Area |
| title_full | Cigarette, cigar and pipe smoking, passive smoke exposure, and risk of pancreatic cancer: a population-based study in the San Francisco Bay Area |
| title_fullStr | Cigarette, cigar and pipe smoking, passive smoke exposure, and risk of pancreatic cancer: a population-based study in the San Francisco Bay Area |
| title_full_unstemmed | Cigarette, cigar and pipe smoking, passive smoke exposure, and risk of pancreatic cancer: a population-based study in the San Francisco Bay Area |
| title_short | Cigarette, cigar and pipe smoking, passive smoke exposure, and risk of pancreatic cancer: a population-based study in the San Francisco Bay Area |
| title_sort | cigarette cigar and pipe smoking passive smoke exposure and risk of pancreatic cancer a population based study in the san francisco bay area |
| url | http://www.biomedcentral.com/1471-2407/11/138 |
| work_keys_str_mv | AT wangfurong cigarettecigarandpipesmokingpassivesmokeexposureandriskofpancreaticcancerapopulationbasedstudyinthesanfranciscobayarea AT hollyelizabetha cigarettecigarandpipesmokingpassivesmokeexposureandriskofpancreaticcancerapopulationbasedstudyinthesanfranciscobayarea AT tranahgregoryj cigarettecigarandpipesmokingpassivesmokeexposureandriskofpancreaticcancerapopulationbasedstudyinthesanfranciscobayarea AT braccipaigem cigarettecigarandpipesmokingpassivesmokeexposureandriskofpancreaticcancerapopulationbasedstudyinthesanfranciscobayarea |