High-Resolution Analysis of Gene Copy Number Alterations in Human Prostate Cancer Using CGH on cDNA Microarrays: Impact of Copy Number on Gene Expression

High-Resolution Analysis of Gene Copy Number Alterations in Human Prostate Cancer Using CGH on cDNA Microarrays: Impact of Copy Number on Gene Expression

Identification of target genes for genetic rearrangements in prostate cancer and the impact of copy number changes on gene expression are currently not well understood. Here, we applied high-resolution comparative genomic hybridization (CGH) on cDNA microarrays for analysis of prostate cancer cell l...

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Bibliographic Details
Main Authors: Maija Wolf, Spyro Mousses, Sampsa Hautaniemi, Ritva Karhu, Pia Huusko, Minna Allinen, Abdel Elkahloun, Outi Monni, Yidong Chen, Anne Kallioniemi, Olli-P Kallioniemi
Format: Article
Language:English
Published: Elsevier 2004-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Copy number alteration
prostate cancer
gene expression
cDNA microarray
CGH microarray
Online Access:http://www.sciencedirect.com/science/article/pii/S147655860480071X

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