A Flow Cytometric Assay to Detect Functional Ganglionic Acetylcholine Receptor Antibodies by Immunomodulation in Autoimmune Autonomic Ganglionopathy

A Flow Cytometric Assay to Detect Functional Ganglionic Acetylcholine Receptor Antibodies by Immunomodulation in Autoimmune Autonomic Ganglionopathy

Autoimmune Autonomic Ganglionopathy (AAG) is an uncommon immune-mediated neurological disease that results in failure of autonomic function and is associated with autoantibodies directed against the ganglionic acetylcholine receptor (gnACHR). The antibodies are routinely detected by immunoprecipitat...

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Bibliographic Details
Main Authors:	Nicolás Urriola, Judith M. Spies, Katrina Blazek, Bethan Lang, Stephen Adelstein
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-06-01
Series:	Frontiers in Immunology
Subjects:	immunoassay flow cytometry—methods neuroimmunology autoimmune autonomic ganglionopathy diagnostic test
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.705292/full

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