Chromatic Pupillometry in Children
Chromatic pupillometry is a technique that is increasingly used to assess retinal disorders. As age may be one of the various factors which can influence the pupillary light reaction, this study aimed to evaluate the pupil responses to colored light stimuli in the pediatric population. Fifty-three c...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-08-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2018.00669/full |
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| author | Sylvain V. Crippa Sylvain V. Crippa Fatima Pedrosa Domellöf Aki Kawasaki |
| author_facet | Sylvain V. Crippa Sylvain V. Crippa Fatima Pedrosa Domellöf Aki Kawasaki |
| author_sort | Sylvain V. Crippa |
| collection | DOAJ |
| description | Chromatic pupillometry is a technique that is increasingly used to assess retinal disorders. As age may be one of the various factors which can influence the pupillary light reaction, this study aimed to evaluate the pupil responses to colored light stimuli in the pediatric population. Fifty-three children with normal vision and without any history of ocular disorders were tested with a portable pupillometer. Four test sequences were used: five dim blue (470 nm) stimuli presented in half log steps ranging from −3.15 to −1.15 log cd/m2 after 3 min of dark adaptation, five red (622 nm) stimuli of −1.15, −0.7, −0.15, 0.3, and 0.85 log cd/m2 after 1 min light adaptation, one bright blue stimulus of 2.2 log cd/m2 and one bright red of 2 log cd/m2. The results were grouped by age: a younger group included 27 children aged from 3 to 10 years old and an older group included 26 from 10 and 1 month to 18 years old. The younger group had a smaller pupil diameter after dark adaptation compared with the older group. A linear regression defining the photopic threshold showed that younger subjects had a higher threshold, e.g., needed a brighter red stimulus to evoke a threshold pupil response comparable that of subjects. Age thus seems to influence outer retinal sensitivity at least as evaluated by the pupillary photopic threshold intensity. The post-illumination pupillary reaction was used as a marker of intrinsic melanopsin activity and did not show any difference between the two age groups. |
| first_indexed | 2024-12-19T23:26:03Z |
| format | Article |
| id | doaj.art-c3e24cdebe5440e097c79a9bfc5086db |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-19T23:26:03Z |
| publishDate | 2018-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-c3e24cdebe5440e097c79a9bfc5086db2022-12-21T20:01:52ZengFrontiers Media S.A.Frontiers in Neurology1664-22952018-08-01910.3389/fneur.2018.00669384230Chromatic Pupillometry in ChildrenSylvain V. Crippa0Sylvain V. Crippa1Fatima Pedrosa Domellöf2Aki Kawasaki3Neuro-Ophthalmology Unit, Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, SwitzerlandGroup for Retinal Disorder Research, Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, SwitzerlandOphthalmology, Department of Clinical Science, Umeå University, Umeå, SwedenNeuro-Ophthalmology Unit, Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, SwitzerlandChromatic pupillometry is a technique that is increasingly used to assess retinal disorders. As age may be one of the various factors which can influence the pupillary light reaction, this study aimed to evaluate the pupil responses to colored light stimuli in the pediatric population. Fifty-three children with normal vision and without any history of ocular disorders were tested with a portable pupillometer. Four test sequences were used: five dim blue (470 nm) stimuli presented in half log steps ranging from −3.15 to −1.15 log cd/m2 after 3 min of dark adaptation, five red (622 nm) stimuli of −1.15, −0.7, −0.15, 0.3, and 0.85 log cd/m2 after 1 min light adaptation, one bright blue stimulus of 2.2 log cd/m2 and one bright red of 2 log cd/m2. The results were grouped by age: a younger group included 27 children aged from 3 to 10 years old and an older group included 26 from 10 and 1 month to 18 years old. The younger group had a smaller pupil diameter after dark adaptation compared with the older group. A linear regression defining the photopic threshold showed that younger subjects had a higher threshold, e.g., needed a brighter red stimulus to evoke a threshold pupil response comparable that of subjects. Age thus seems to influence outer retinal sensitivity at least as evaluated by the pupillary photopic threshold intensity. The post-illumination pupillary reaction was used as a marker of intrinsic melanopsin activity and did not show any difference between the two age groups.https://www.frontiersin.org/article/10.3389/fneur.2018.00669/fullpupilchromatic pupillometrychildrenpupillary light reactiongrowth |
| spellingShingle | Sylvain V. Crippa Sylvain V. Crippa Fatima Pedrosa Domellöf Aki Kawasaki Chromatic Pupillometry in Children Frontiers in Neurology pupil chromatic pupillometry children pupillary light reaction growth |
| title | Chromatic Pupillometry in Children |
| title_full | Chromatic Pupillometry in Children |
| title_fullStr | Chromatic Pupillometry in Children |
| title_full_unstemmed | Chromatic Pupillometry in Children |
| title_short | Chromatic Pupillometry in Children |
| title_sort | chromatic pupillometry in children |
| topic | pupil chromatic pupillometry children pupillary light reaction growth |
| url | https://www.frontiersin.org/article/10.3389/fneur.2018.00669/full |
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