Zearalenone Does Not Show Genotoxic Effects in the <i>Drosophila melanogaster</i> Wing Spot Test, but It Induces Oxidative Imbalance, Development, and Fecundity Alterations

Zearalenone Does Not Show Genotoxic Effects in the <i>Drosophila melanogaster</i> Wing Spot Test, but It Induces Oxidative Imbalance, Development, and Fecundity Alterations

Zearalenone (ZEN) is a non-steroidal mycoestrogen produced by the <i>Fusarium</i> genus. ZEN and its metabolites compete with 17-beta estradiol for cytosolic estrogen receptors, causing reproductive alterations in vertebrates. ZEN has also been associated with toxic and genotoxic effects...

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Bibliographic Details
Main Authors: Luis Felipe Santos-Cruz, Alberto Ponciano-Gómez, Juan Tomás Torres-Gregorio, Bertha Guadalupe Ramírez-Cruz, Gerardo Vázquez-Gómez, Luis Barbo Hernández-Portilla, Cesar Mateo Flores-Ortiz, Irma Elena Dueñas-García, María Eugenia Heres-Pulido, Laura Castañeda-Partida, Ángel Durán-Díaz, Myriam Campos-Aguilar, Santiago Cristobal Sigrist-Flores, Elías Piedra-Ibarra
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Toxins
Subjects:
zearalenone
<i>Drosophila melanogaster</i>
oxidative stress
cytochromes P450
wing spot test
Online Access:https://www.mdpi.com/2072-6651/15/6/358

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