Deep Recursive Bayesian Tracking for Fully Automatic Centerline Extraction of Coronary Arteries in CT Images

Extraction of coronary arteries in coronary computed tomography (CT) angiography is a prerequisite for the quantification of coronary lesions. In this study, we propose a tracking method combining a deep convolutional neural network (DNN) and particle filtering method to identify the trajectories fr...

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Main Author: Byunghwan Jeon
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/21/18/6087
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author Byunghwan Jeon
author_facet Byunghwan Jeon
author_sort Byunghwan Jeon
collection DOAJ
description Extraction of coronary arteries in coronary computed tomography (CT) angiography is a prerequisite for the quantification of coronary lesions. In this study, we propose a tracking method combining a deep convolutional neural network (DNN) and particle filtering method to identify the trajectories from the coronary ostium to each distal end from 3D CT images. The particle filter, as a non-linear approximator, is an appropriate tracking framework for such thin and elongated structures; however, the robust ‘vesselness’ measurement is essential for extracting coronary centerlines. Importantly, we employed the DNN to robustly measure the vesselness using patch images, and we integrated softmax values to the likelihood function in our particle filtering framework. Tangent patches represent cross-sections of coronary arteries of circular shapes. Thus, 2D tangent patches are assumed to include enough features of coronary arteries, and the use of 2D patches significantly reduces computational complexity. Because coronary vasculature has multiple bifurcations, we also modeled a method to detect branching sites by clustering the particle locations. The proposed method is compared with three commercial workstations and two conventional methods from the academic literature.
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spelling doaj.art-c3e66e288ddb4a029577ba55eb7c9b9b2023-11-22T15:11:25ZengMDPI AGSensors1424-82202021-09-012118608710.3390/s21186087Deep Recursive Bayesian Tracking for Fully Automatic Centerline Extraction of Coronary Arteries in CT ImagesByunghwan Jeon0School of Computer Science, Kyungil University, Gyeongsan 38428, KoreaExtraction of coronary arteries in coronary computed tomography (CT) angiography is a prerequisite for the quantification of coronary lesions. In this study, we propose a tracking method combining a deep convolutional neural network (DNN) and particle filtering method to identify the trajectories from the coronary ostium to each distal end from 3D CT images. The particle filter, as a non-linear approximator, is an appropriate tracking framework for such thin and elongated structures; however, the robust ‘vesselness’ measurement is essential for extracting coronary centerlines. Importantly, we employed the DNN to robustly measure the vesselness using patch images, and we integrated softmax values to the likelihood function in our particle filtering framework. Tangent patches represent cross-sections of coronary arteries of circular shapes. Thus, 2D tangent patches are assumed to include enough features of coronary arteries, and the use of 2D patches significantly reduces computational complexity. Because coronary vasculature has multiple bifurcations, we also modeled a method to detect branching sites by clustering the particle locations. The proposed method is compared with three commercial workstations and two conventional methods from the academic literature.https://www.mdpi.com/1424-8220/21/18/6087coronary arterydeep learningtrackingcomputed tomography
spellingShingle Byunghwan Jeon
Deep Recursive Bayesian Tracking for Fully Automatic Centerline Extraction of Coronary Arteries in CT Images
Sensors
coronary artery
deep learning
tracking
computed tomography
title Deep Recursive Bayesian Tracking for Fully Automatic Centerline Extraction of Coronary Arteries in CT Images
title_full Deep Recursive Bayesian Tracking for Fully Automatic Centerline Extraction of Coronary Arteries in CT Images
title_fullStr Deep Recursive Bayesian Tracking for Fully Automatic Centerline Extraction of Coronary Arteries in CT Images
title_full_unstemmed Deep Recursive Bayesian Tracking for Fully Automatic Centerline Extraction of Coronary Arteries in CT Images
title_short Deep Recursive Bayesian Tracking for Fully Automatic Centerline Extraction of Coronary Arteries in CT Images
title_sort deep recursive bayesian tracking for fully automatic centerline extraction of coronary arteries in ct images
topic coronary artery
deep learning
tracking
computed tomography
url https://www.mdpi.com/1424-8220/21/18/6087
work_keys_str_mv AT byunghwanjeon deeprecursivebayesiantrackingforfullyautomaticcenterlineextractionofcoronaryarteriesinctimages