Optimization of E. coli Cultivation Model Parameters Using Firefly Algorithm
In this paper, a novel meta-heuristics algorithm, namely the Firefly Algorithm (FA), is adapted and applied for a model parameter identification of an E. coli fed-batch cultivation process. A system of ordinary nonlinear differential equations is used to model the biomass growth and substrate utiliz...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bulgarian Academy of Sciences
2012-04-01
|
| Series: | International Journal Bioautomation |
| Subjects: | |
| Online Access: | http://www.clbme.bas.bg/bioautomation/2012/vol_16.1/files/16.1_03.pdf |
| _version_ | 1818244216136925184 |
|---|---|
| author | Olympia Roeva Olympia Roeva |
| author_facet | Olympia Roeva Olympia Roeva |
| author_sort | Olympia Roeva |
| collection | DOAJ |
| description | In this paper, a novel meta-heuristics algorithm, namely the Firefly Algorithm (FA), is adapted and applied for a model parameter identification of an E. coli fed-batch cultivation process. A system of ordinary nonlinear differential equations is used to model the biomass growth and substrate utilization. Parameter optimization is performed using real experimental data set from an E. coli MC4110 fed-batch cultivation process. The FA adjustments are done based on several pre-tests according to the optimization problem considered here. The simulation results indicate that the applied algorithm is effective and efficient. As a result, a model with high degree of accuracy is obtained applying the FA. |
| first_indexed | 2024-12-12T14:13:29Z |
| format | Article |
| id | doaj.art-c3e88fbc94084f0ebb2e6f62213a59ac |
| institution | Directory Open Access Journal |
| issn | 1314-1902 1314-2321 |
| language | English |
| last_indexed | 2024-12-12T14:13:29Z |
| publishDate | 2012-04-01 |
| publisher | Bulgarian Academy of Sciences |
| record_format | Article |
| series | International Journal Bioautomation |
| spelling | doaj.art-c3e88fbc94084f0ebb2e6f62213a59ac2022-12-22T00:21:59ZengBulgarian Academy of SciencesInternational Journal Bioautomation1314-19021314-23212012-04-011612332Optimization of E. coli Cultivation Model Parameters Using Firefly AlgorithmOlympia RoevaOlympia RoevaIn this paper, a novel meta-heuristics algorithm, namely the Firefly Algorithm (FA), is adapted and applied for a model parameter identification of an E. coli fed-batch cultivation process. A system of ordinary nonlinear differential equations is used to model the biomass growth and substrate utilization. Parameter optimization is performed using real experimental data set from an E. coli MC4110 fed-batch cultivation process. The FA adjustments are done based on several pre-tests according to the optimization problem considered here. The simulation results indicate that the applied algorithm is effective and efficient. As a result, a model with high degree of accuracy is obtained applying the FA.http://www.clbme.bas.bg/bioautomation/2012/vol_16.1/files/16.1_03.pdfOptimizationFirefly algorithmE. coli cultivationIdentificationModel parameters |
| spellingShingle | Olympia Roeva Olympia Roeva Optimization of E. coli Cultivation Model Parameters Using Firefly Algorithm International Journal Bioautomation Optimization Firefly algorithm E. coli cultivation Identification Model parameters |
| title | Optimization of E. coli Cultivation Model Parameters Using Firefly Algorithm |
| title_full | Optimization of E. coli Cultivation Model Parameters Using Firefly Algorithm |
| title_fullStr | Optimization of E. coli Cultivation Model Parameters Using Firefly Algorithm |
| title_full_unstemmed | Optimization of E. coli Cultivation Model Parameters Using Firefly Algorithm |
| title_short | Optimization of E. coli Cultivation Model Parameters Using Firefly Algorithm |
| title_sort | optimization of e coli cultivation model parameters using firefly algorithm |
| topic | Optimization Firefly algorithm E. coli cultivation Identification Model parameters |
| url | http://www.clbme.bas.bg/bioautomation/2012/vol_16.1/files/16.1_03.pdf |
| work_keys_str_mv | AT olympiaroeva optimizationofecolicultivationmodelparametersusingfireflyalgorithm AT olympiaroeva optimizationofecolicultivationmodelparametersusingfireflyalgorithm |