Inflammatory and cytotoxic effects of bifenthrin in primary microglia and organotypic hippocampal slice cultures

Inflammatory and cytotoxic effects of bifenthrin in primary microglia and organotypic hippocampal slice cultures

Abstract Background Pyrethroids, such as bifenthrin (BF), are among the most widely used class of insecticides that pose serious risks to human and wildlife health. Pyrethroids are proposed to affect astrocytic functions and to cause neuron injury in the central nervous system (CNS). Microglia are k...

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Bibliographic Details
Main Authors: Brahim Gargouri, Nizar M. Yousif, Michèle Bouchard, Hamadi Fetoui, Bernd L. Fiebich
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Neuroinflammation
Subjects:
Bifenthrin
Microglia
Oxidative stress
OHSCs
Nrf-2
NF-kappaB
Online Access:http://link.springer.com/article/10.1186/s12974-018-1198-1

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