Technical features of Norwood procedure as the most important factor, affecting the outcome of treatment of single-ventricle patients with obstructed systemic output
The objective was to improveNorwood procedure outcomes by discovering optimal surgical technique and perfusion strategy.Material and methods. Results of treatment of single-ventricle patients with obstructed systemic output during 2005–2017 were analyzed (64 patients). 61 patients underwentNorwood p...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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Pavlov First Saint Petersburg State Medical University
2019-02-01
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| Series: | Вестник хирургии имени И.И. Грекова |
| Subjects: | |
| Online Access: | https://www.vestnik-grekova.ru/jour/article/view/1187 |
| _version_ | 1797877610193092608 |
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| author | A. A. Avramenko S. M. Khokhlunov |
| author_facet | A. A. Avramenko S. M. Khokhlunov |
| author_sort | A. A. Avramenko |
| collection | DOAJ |
| description | The objective was to improveNorwood procedure outcomes by discovering optimal surgical technique and perfusion strategy.Material and methods. Results of treatment of single-ventricle patients with obstructed systemic output during 2005–2017 were analyzed (64 patients). 61 patients underwentNorwood procedure. Outcomes were compared between groups with different perfusion strategies and different methods of aortic arch reconstruction.Results. Mortality in two-regional perfusion group was 23 %, in group of circulatory arrest and selective cerebral perfusion – 53 % (p=0.020). Early aortic obstruction was a risk factor of mortality (p=0.024). Median time of freedom from obstruction of aorta was 3 days in xenopericardium group, 76 days in pulmonary allograft group, and 390 days in isthmus resection and pulmonary allograft group (p=0.002).Conclusion. Two-regional perfusion and aortic arch repair with pulmonary allograft patch after isthmus resection are our methods of choice as they allow to reduce the incidence of complications afterNorwood procedure. |
| first_indexed | 2024-04-10T02:19:53Z |
| format | Article |
| id | doaj.art-c3eae8dde35a42b9985e82d8ffb5868d |
| institution | Directory Open Access Journal |
| issn | 0042-4625 |
| language | Russian |
| last_indexed | 2024-04-10T02:19:53Z |
| publishDate | 2019-02-01 |
| publisher | Pavlov First Saint Petersburg State Medical University |
| record_format | Article |
| series | Вестник хирургии имени И.И. Грекова |
| spelling | doaj.art-c3eae8dde35a42b9985e82d8ffb5868d2023-03-13T08:09:17ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252019-02-011781111610.24884/0042-4625-2019-178-1-11-16986Technical features of Norwood procedure as the most important factor, affecting the outcome of treatment of single-ventricle patients with obstructed systemic outputA. A. Avramenko0S. M. Khokhlunov1Samara State Medical UniversitySamara State Medical UniversityThe objective was to improveNorwood procedure outcomes by discovering optimal surgical technique and perfusion strategy.Material and methods. Results of treatment of single-ventricle patients with obstructed systemic output during 2005–2017 were analyzed (64 patients). 61 patients underwentNorwood procedure. Outcomes were compared between groups with different perfusion strategies and different methods of aortic arch reconstruction.Results. Mortality in two-regional perfusion group was 23 %, in group of circulatory arrest and selective cerebral perfusion – 53 % (p=0.020). Early aortic obstruction was a risk factor of mortality (p=0.024). Median time of freedom from obstruction of aorta was 3 days in xenopericardium group, 76 days in pulmonary allograft group, and 390 days in isthmus resection and pulmonary allograft group (p=0.002).Conclusion. Two-regional perfusion and aortic arch repair with pulmonary allograft patch after isthmus resection are our methods of choice as they allow to reduce the incidence of complications afterNorwood procedure.https://www.vestnik-grekova.ru/jour/article/view/1187congenital heart defectshypoplastic left heart syndromenorwood procedureselective cerebral perfusionmyocardial protection |
| spellingShingle | A. A. Avramenko S. M. Khokhlunov Technical features of Norwood procedure as the most important factor, affecting the outcome of treatment of single-ventricle patients with obstructed systemic output Вестник хирургии имени И.И. Грекова congenital heart defects hypoplastic left heart syndrome norwood procedure selective cerebral perfusion myocardial protection |
| title | Technical features of Norwood procedure as the most important factor, affecting the outcome of treatment of single-ventricle patients with obstructed systemic output |
| title_full | Technical features of Norwood procedure as the most important factor, affecting the outcome of treatment of single-ventricle patients with obstructed systemic output |
| title_fullStr | Technical features of Norwood procedure as the most important factor, affecting the outcome of treatment of single-ventricle patients with obstructed systemic output |
| title_full_unstemmed | Technical features of Norwood procedure as the most important factor, affecting the outcome of treatment of single-ventricle patients with obstructed systemic output |
| title_short | Technical features of Norwood procedure as the most important factor, affecting the outcome of treatment of single-ventricle patients with obstructed systemic output |
| title_sort | technical features of norwood procedure as the most important factor affecting the outcome of treatment of single ventricle patients with obstructed systemic output |
| topic | congenital heart defects hypoplastic left heart syndrome norwood procedure selective cerebral perfusion myocardial protection |
| url | https://www.vestnik-grekova.ru/jour/article/view/1187 |
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