Hepatocyte miR-34a is a key regulator in the development and progression of non-alcoholic fatty liver disease

Hepatocyte miR-34a is a key regulator in the development and progression of non-alcoholic fatty liver disease

Objective: Hepatic miR-34a expression is elevated in diet-induced or genetically obese mice and patients with non-alcoholic steatohepatitis (NASH), yet hepatocyte miR-34a's role in the progression of non-alcoholic fatty liver disease (NAFLD) from non-alcoholic fatty liver (NAFL) to NASH remains...

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Bibliographic Details
Main Authors: Yanyong Xu, Yingdong Zhu, Shuwei Hu, Xiaoli Pan, Fathima Cassim Bawa, Helen H. Wang, David Q.-H. Wang, Liya Yin, Yanqiao Zhang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Molecular Metabolism
Subjects:
miR-34a
NAFLD
Lipogenesis
Lipid absorption
Bile acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821000892

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