Discovery of novel thiosemicarbazone derivatives with potent and selective anti-Candida glabrata activity

AbstractA series of 21 novel compounds containing a thiosemicarbazone moiety were designed and synthesised based on hit compound 1 from our in-house compound library screening. Most compounds showed potent antifungal activity in vitro against seven common pathogenic fungi. Notably, all compounds sho...

Full description

Bibliographic Details
Main Authors: Xianru Li, Liping Li, Haonan Zhang, Xiaochen Chi, Yuanying Jiang, Tingjunhong Ni
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2023.2202362

Similar Items