Serum IL‐6 and MCP‐1 concentrations in dogs with lymphoma before and after doxorubicin treatment as a potential marker of cellular senescence

Serum IL‐6 and MCP‐1 concentrations in dogs with lymphoma before and after doxorubicin treatment as a potential marker of cellular senescence

Abstract Background Chemotherapy can induce cellular senescence and a secretory phenotype characterized by an increased expression of inflammatory cytokines, such as IL‐6 and MCP‐1. Increased IL‐6 and MCP‐1 serum concentrations have been documented in dogs with lymphoma, but no studies have evaluate...

Full description

Bibliographic Details
Main Authors: Brittany L. Evans, Joelle M. Fenger, Greg Ballash, Megan Brown
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Veterinary Medicine and Science
Subjects:
canine
chemotherapy
cytokine
toxicity
Online Access:https://doi.org/10.1002/vms3.633

Similar Items

Similar Items