Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity
ABSTRACT Visceral Leishmaniasis (VL) is a potentially fatal disease and may be associated with primary or acquired immunodeficiencies. There are few reports, in the literature, of inborn errors of immunity. Here, we report two cases of VL as a marker of inborn errors of immunity, namely, GATA2 and R...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2023-11-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822023000100710&tlng=en |
| _version_ | 1827762955140202496 |
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| author | Daniel Gleison Carvalho Dewton de Moraes Vasconcelos Andreia Cristiane Rangel Santos Jose Angelo Lauletta Lindoso |
| author_facet | Daniel Gleison Carvalho Dewton de Moraes Vasconcelos Andreia Cristiane Rangel Santos Jose Angelo Lauletta Lindoso |
| author_sort | Daniel Gleison Carvalho |
| collection | DOAJ |
| description | ABSTRACT Visceral Leishmaniasis (VL) is a potentially fatal disease and may be associated with primary or acquired immunodeficiencies. There are few reports, in the literature, of inborn errors of immunity. Here, we report two cases of VL as a marker of inborn errors of immunity, namely, GATA2 and RAB27A deficiency. Our data suggest that VL patients should be screened for primary immunodeficiency, particularly in cases of VL relapse. |
| first_indexed | 2024-03-11T10:44:21Z |
| format | Article |
| id | doaj.art-c3f17ebc123444bf98f0f801c6080064 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-03-11T10:44:21Z |
| publishDate | 2023-11-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-c3f17ebc123444bf98f0f801c60800642023-11-14T07:45:07ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492023-11-015610.1590/0037-8682-0322-2023Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of ImmunityDaniel Gleison Carvalhohttps://orcid.org/0000-0003-3509-7466Dewton de Moraes Vasconceloshttps://orcid.org/0000-0002-3930-3354Andreia Cristiane Rangel Santoshttps://orcid.org/0000-0002-0577-1117Jose Angelo Lauletta Lindosohttps://orcid.org/0000-0002-4405-4401ABSTRACT Visceral Leishmaniasis (VL) is a potentially fatal disease and may be associated with primary or acquired immunodeficiencies. There are few reports, in the literature, of inborn errors of immunity. Here, we report two cases of VL as a marker of inborn errors of immunity, namely, GATA2 and RAB27A deficiency. Our data suggest that VL patients should be screened for primary immunodeficiency, particularly in cases of VL relapse.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822023000100710&tlng=enVisceral LeishmaniasisPrimary ImmunodeficiencyCellular immunodeficiency |
| spellingShingle | Daniel Gleison Carvalho Dewton de Moraes Vasconcelos Andreia Cristiane Rangel Santos Jose Angelo Lauletta Lindoso Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity Revista da Sociedade Brasileira de Medicina Tropical Visceral Leishmaniasis Primary Immunodeficiency Cellular immunodeficiency |
| title | Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity |
| title_full | Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity |
| title_fullStr | Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity |
| title_full_unstemmed | Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity |
| title_short | Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity |
| title_sort | visceral leishmaniasis revealing undiagnosed inborn errors of immunity |
| topic | Visceral Leishmaniasis Primary Immunodeficiency Cellular immunodeficiency |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822023000100710&tlng=en |
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