Association of HLA diversity with the risk of 25 cancers in the UK BiobankResearch in context

Association of HLA diversity with the risk of 25 cancers in the UK BiobankResearch in context

Summary: Background: The human leukocyte antigen (HLA) is a highly polymorphic region, and HLA diversity may play a role in presenting tumour-associated peptides and inducing immune responses. However, the effect of HLA diversity on cancers has not been fully assessed. We aimed to explore the role...

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Bibliographic Details
Main Authors:	Qiao-Ling Wang, Tong-Min Wang, Chang-Mi Deng, Wen-Li Zhang, Yong-Qiao He, Wen-Qiong Xue, Ying Liao, Da-Wei Yang, Mei-Qi Zheng, Wei-Hua Jia
Format:	Article
Language:	English
Published:	Elsevier 2023-06-01
Series:	EBioMedicine
Subjects:	UK Biobank HLA heterozygosity HLA evolutionary Divergence Cancer susceptibility
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396423001536

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