Association of HLA diversity with the risk of 25 cancers in the UK BiobankResearch in context

Association of HLA diversity with the risk of 25 cancers in the UK BiobankResearch in context

Summary: Background: The human leukocyte antigen (HLA) is a highly polymorphic region, and HLA diversity may play a role in presenting tumour-associated peptides and inducing immune responses. However, the effect of HLA diversity on cancers has not been fully assessed. We aimed to explore the role...

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Autori principali:	Qiao-Ling Wang, Tong-Min Wang, Chang-Mi Deng, Wen-Li Zhang, Yong-Qiao He, Wen-Qiong Xue, Ying Liao, Da-Wei Yang, Mei-Qi Zheng, Wei-Hua Jia
Natura:	Articolo
Lingua:	English
Pubblicazione:	Elsevier 2023-06-01
Serie:	EBioMedicine
Soggetti:	UK Biobank HLA heterozygosity HLA evolutionary Divergence Cancer susceptibility
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2352396423001536

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