Association of HLA diversity with the risk of 25 cancers in the UK BiobankResearch in context

Summary: Background: The human leukocyte antigen (HLA) is a highly polymorphic region, and HLA diversity may play a role in presenting tumour-associated peptides and inducing immune responses. However, the effect of HLA diversity on cancers has not been fully assessed. We aimed to explore the role...

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Main Authors: Qiao-Ling Wang, Tong-Min Wang, Chang-Mi Deng, Wen-Li Zhang, Yong-Qiao He, Wen-Qiong Xue, Ying Liao, Da-Wei Yang, Mei-Qi Zheng, Wei-Hua Jia
Format: Article
Jezik:English
Izdano: Elsevier 2023-06-01
Serija:EBioMedicine
Teme:
Online dostop:http://www.sciencedirect.com/science/article/pii/S2352396423001536