Association of subjective health and abnormal cervical cytology in Japanese pregnant women: An adjunct study of the Japan Environment and Children's Study
This study examines the association between abnormal cervical cytology and subjective health in pregnant women, as an adjunct to the Japan Environment and Children's Study, which cross-sectionally analyzed a subset of the prospective cohort. A total of 3024 pregnant women at a childbirth facili...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | Preventive Medicine Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211335521002151 |
| _version_ | 1818462174582931456 |
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| author | Satomi Sasaki Hirohito Metoki Michihiro Satoh Takahisa Murakami Kaou Tanoue Kosuke Tanaka Noriyuki Iwama Zen Watanabe Satoshi Okamoto Masatoshi Saito Junichi Sugawara Kiyoshi Ito Nobuo Yaegashi |
| author_facet | Satomi Sasaki Hirohito Metoki Michihiro Satoh Takahisa Murakami Kaou Tanoue Kosuke Tanaka Noriyuki Iwama Zen Watanabe Satoshi Okamoto Masatoshi Saito Junichi Sugawara Kiyoshi Ito Nobuo Yaegashi |
| author_sort | Satomi Sasaki |
| collection | DOAJ |
| description | This study examines the association between abnormal cervical cytology and subjective health in pregnant women, as an adjunct to the Japan Environment and Children's Study, which cross-sectionally analyzed a subset of the prospective cohort. A total of 3024 pregnant women at a childbirth facility whose medical records of cervical cytology in the first trimester of pregnancy were transcribed and who responded to the subjective health questionnaire were included herein. They were classified into excellent, good, fair, and poor groups based on their subjective health. Cervical cytology results obtained from perinatal medical records were classified into normal and abnormal cytology based on the Bethesda classification. Logistic regression analysis adjusted for baseline characteristics, including age, pre-pregnancy body mass index, parity, and other possible confounding factors, was used. Of 3024 pregnant women, 106 (3.5%) had abnormal cytology, with the prevalence being 1.3%, 3.7%, 3.9%, and 4.0%, respectively (p = 0.055) in the poor, fair, good, and excellent groups. The baseline characteristics, namely age, history of gynecological diseases, Kessler 6-item psychological distress scale score, and history of mental illness, were significantly different between groups. Compared to the poor group, the other three groups had a significantly higher abnormal cytology risk after adjusting for confounding factors (Fair: adjusted OR [aOR] = 3.6, 95% CI [1.0–12.1]; Good: aOR = 4.6 [1.3–15.5]; Excellent: aOR = 4.6 [1.2–17.8]). This study encourages young women to undergo cervical cancer screening because they are at risk for cervical cancer even if they think that they are healthy, and preventive activities like regular screening are essential. |
| first_indexed | 2024-12-14T23:57:51Z |
| format | Article |
| id | doaj.art-c3f7dd568e43419282f4d557bea1811d |
| institution | Directory Open Access Journal |
| issn | 2211-3355 |
| language | English |
| last_indexed | 2024-12-14T23:57:51Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Preventive Medicine Reports |
| spelling | doaj.art-c3f7dd568e43419282f4d557bea1811d2022-12-21T22:43:02ZengElsevierPreventive Medicine Reports2211-33552021-12-0124101525Association of subjective health and abnormal cervical cytology in Japanese pregnant women: An adjunct study of the Japan Environment and Children's StudySatomi Sasaki0Hirohito Metoki1Michihiro Satoh2Takahisa Murakami3Kaou Tanoue4Kosuke Tanaka5Noriyuki Iwama6Zen Watanabe7Satoshi Okamoto8Masatoshi Saito9Junichi Sugawara10Kiyoshi Ito11Nobuo Yaegashi12Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, JapanDivision of Public Health, Hygiene and Epidemiology, Tohoku Medical Pharmaceutical University, 1-15-1 Fukumuro, Sendai, Miyagi 983-8536, Japan; Tohoku Medical Megabank Organization, Tohoku University, 2-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, Japan; Corresponding author at: Division of Public Health, Hygiene and Epidemiology, Tohoku Medical and Pharmaceutical University, Fukurmuro 1-15-1, Miyagino-ku, Sendai 983-8536, Japan.Division of Public Health, Hygiene and Epidemiology, Tohoku Medical Pharmaceutical University, 1-15-1 Fukumuro, Sendai, Miyagi 983-8536, JapanDivision of Public Health, Hygiene and Epidemiology, Tohoku Medical Pharmaceutical University, 1-15-1 Fukumuro, Sendai, Miyagi 983-8536, JapanDepartment of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Obstetrics and Gynecology, Hachinohe City Hospital, 3-1-1, Tamukai, Hachinohe, Aomori 031-8555, JapanDepartment of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Clinical Laboratory, Tohoku Kosai Hospital, 2-3-11, Kokubun-machi, Aoba-ku, Sendai, Miyagi 980-0803, JapanDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan; Department of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan; Tohoku Medical Megabank Organization, Tohoku University, 2-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, JapanTohoku Medical Megabank Organization, Tohoku University, 2-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, Japan; Department of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan; Department of Disaster Obstetrics and Gynecology, International Research Institute of Disaster Science (IRIDeS), Tohoku University, 2-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, JapanDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan; Tohoku Medical Megabank Organization, Tohoku University, 2-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, Japan; Department of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, JapanThis study examines the association between abnormal cervical cytology and subjective health in pregnant women, as an adjunct to the Japan Environment and Children's Study, which cross-sectionally analyzed a subset of the prospective cohort. A total of 3024 pregnant women at a childbirth facility whose medical records of cervical cytology in the first trimester of pregnancy were transcribed and who responded to the subjective health questionnaire were included herein. They were classified into excellent, good, fair, and poor groups based on their subjective health. Cervical cytology results obtained from perinatal medical records were classified into normal and abnormal cytology based on the Bethesda classification. Logistic regression analysis adjusted for baseline characteristics, including age, pre-pregnancy body mass index, parity, and other possible confounding factors, was used. Of 3024 pregnant women, 106 (3.5%) had abnormal cytology, with the prevalence being 1.3%, 3.7%, 3.9%, and 4.0%, respectively (p = 0.055) in the poor, fair, good, and excellent groups. The baseline characteristics, namely age, history of gynecological diseases, Kessler 6-item psychological distress scale score, and history of mental illness, were significantly different between groups. Compared to the poor group, the other three groups had a significantly higher abnormal cytology risk after adjusting for confounding factors (Fair: adjusted OR [aOR] = 3.6, 95% CI [1.0–12.1]; Good: aOR = 4.6 [1.3–15.5]; Excellent: aOR = 4.6 [1.2–17.8]). This study encourages young women to undergo cervical cancer screening because they are at risk for cervical cancer even if they think that they are healthy, and preventive activities like regular screening are essential.http://www.sciencedirect.com/science/article/pii/S2211335521002151Cervical cancerPregnancyHPVScreeningSubjective health |
| spellingShingle | Satomi Sasaki Hirohito Metoki Michihiro Satoh Takahisa Murakami Kaou Tanoue Kosuke Tanaka Noriyuki Iwama Zen Watanabe Satoshi Okamoto Masatoshi Saito Junichi Sugawara Kiyoshi Ito Nobuo Yaegashi Association of subjective health and abnormal cervical cytology in Japanese pregnant women: An adjunct study of the Japan Environment and Children's Study Preventive Medicine Reports Cervical cancer Pregnancy HPV Screening Subjective health |
| title | Association of subjective health and abnormal cervical cytology in Japanese pregnant women: An adjunct study of the Japan Environment and Children's Study |
| title_full | Association of subjective health and abnormal cervical cytology in Japanese pregnant women: An adjunct study of the Japan Environment and Children's Study |
| title_fullStr | Association of subjective health and abnormal cervical cytology in Japanese pregnant women: An adjunct study of the Japan Environment and Children's Study |
| title_full_unstemmed | Association of subjective health and abnormal cervical cytology in Japanese pregnant women: An adjunct study of the Japan Environment and Children's Study |
| title_short | Association of subjective health and abnormal cervical cytology in Japanese pregnant women: An adjunct study of the Japan Environment and Children's Study |
| title_sort | association of subjective health and abnormal cervical cytology in japanese pregnant women an adjunct study of the japan environment and children s study |
| topic | Cervical cancer Pregnancy HPV Screening Subjective health |
| url | http://www.sciencedirect.com/science/article/pii/S2211335521002151 |
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