THE USE OF MASS SPECTROMETRIC ANALYSIS FOR THE DETECTION OF BACTERIAL TOXINS
Toxins - molecular weight compounds produced by microorganisms, animals, plants and possessing antigene properties. Recently due to the perceived threat of terrorist actions identification of a number of bacterial toxins is especially important. A new approach in the identification of toxins associa...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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Central Research Institute for Epidemiology
2018-02-01
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| Series: | Журнал микробиологии, эпидемиологии и иммунобиологии |
| Subjects: | |
| Online Access: | https://microbiol.elpub.ru/jour/article/view/253 |
| _version_ | 1828435037806133248 |
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| author | M. V. Poleeva O. S. Chemisova |
| author_facet | M. V. Poleeva O. S. Chemisova |
| author_sort | M. V. Poleeva |
| collection | DOAJ |
| description | Toxins - molecular weight compounds produced by microorganisms, animals, plants and possessing antigene properties. Recently due to the perceived threat of terrorist actions identification of a number of bacterial toxins is especially important. A new approach in the identification of toxins associated with the development of mass spectrometry and can be successfully used for analysis of most environmental toxins. The method of MALDI-MS allows the detection of toxins such as Shiga-toxin Escherichia coli, delta-toxin of Staphylococcus aureus, Bacillus cereus particular, botulinum neurotoxin, cholera toxin. Analytical and diagnostic characteristics of the method, the simplicity and speed studies indicate the long term implementation of a method in the practice of laboratory diagnostics in determining toxinproducing of the studied microorganisms. |
| first_indexed | 2024-12-10T18:59:22Z |
| format | Article |
| id | doaj.art-c3f855c42c8146ad98a1bcb006d6e8bd |
| institution | Directory Open Access Journal |
| issn | 0372-9311 2686-7613 |
| language | Russian |
| last_indexed | 2024-12-10T18:59:22Z |
| publishDate | 2018-02-01 |
| publisher | Central Research Institute for Epidemiology |
| record_format | Article |
| series | Журнал микробиологии, эпидемиологии и иммунобиологии |
| spelling | doaj.art-c3f855c42c8146ad98a1bcb006d6e8bd2022-12-22T01:37:02ZrusCentral Research Institute for EpidemiologyЖурнал микробиологии, эпидемиологии и иммунобиологии0372-93112686-76132018-02-01019310110.36233/0372-9311-2018-1-93-101253THE USE OF MASS SPECTROMETRIC ANALYSIS FOR THE DETECTION OF BACTERIAL TOXINSM. V. Poleeva0O. S. Chemisova1Rostov-on-Don Research Institute for Plague ControlRostov-on-Don Research Institute for Plague ControlToxins - molecular weight compounds produced by microorganisms, animals, plants and possessing antigene properties. Recently due to the perceived threat of terrorist actions identification of a number of bacterial toxins is especially important. A new approach in the identification of toxins associated with the development of mass spectrometry and can be successfully used for analysis of most environmental toxins. The method of MALDI-MS allows the detection of toxins such as Shiga-toxin Escherichia coli, delta-toxin of Staphylococcus aureus, Bacillus cereus particular, botulinum neurotoxin, cholera toxin. Analytical and diagnostic characteristics of the method, the simplicity and speed studies indicate the long term implementation of a method in the practice of laboratory diagnostics in determining toxinproducing of the studied microorganisms.https://microbiol.elpub.ru/jour/article/view/253maldi-ms спекрометрический анализmascotmaldi-ms spectrometric analysistime-of-flight mass spectrometrybacterial toxinsmatrixcalibrantmascotidentification |
| spellingShingle | M. V. Poleeva O. S. Chemisova THE USE OF MASS SPECTROMETRIC ANALYSIS FOR THE DETECTION OF BACTERIAL TOXINS Журнал микробиологии, эпидемиологии и иммунобиологии maldi-ms спекрометрический анализ mascot maldi-ms spectrometric analysis time-of-flight mass spectrometry bacterial toxins matrix calibrant mascot identification |
| title | THE USE OF MASS SPECTROMETRIC ANALYSIS FOR THE DETECTION OF BACTERIAL TOXINS |
| title_full | THE USE OF MASS SPECTROMETRIC ANALYSIS FOR THE DETECTION OF BACTERIAL TOXINS |
| title_fullStr | THE USE OF MASS SPECTROMETRIC ANALYSIS FOR THE DETECTION OF BACTERIAL TOXINS |
| title_full_unstemmed | THE USE OF MASS SPECTROMETRIC ANALYSIS FOR THE DETECTION OF BACTERIAL TOXINS |
| title_short | THE USE OF MASS SPECTROMETRIC ANALYSIS FOR THE DETECTION OF BACTERIAL TOXINS |
| title_sort | use of mass spectrometric analysis for the detection of bacterial toxins |
| topic | maldi-ms спекрометрический анализ mascot maldi-ms spectrometric analysis time-of-flight mass spectrometry bacterial toxins matrix calibrant mascot identification |
| url | https://microbiol.elpub.ru/jour/article/view/253 |
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