Apolipoprotein B(Arg3500—-Gln) allele specific polymerase chain reaction: large-scale screening of pooled blood samples.
A two-step polymerase chain reaction (PCR) method for the rapid detection of the apolipoprotein B(Arg3500—-Gln) mutation in a mixture of pooled blood samples is described. In the first step PCR, a short gene fragment surrounding codon 3500 is amplified. Subsequently the reaction product is subjected...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1992-10-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520414105 |