Molecular markers in sex hormone pathway genes associated with the efficacy of androgen-deprivation therapy for prostate cancer.

Molecular markers in sex hormone pathway genes associated with the efficacy of androgen-deprivation therapy for prostate cancer.

Although most advanced prostate cancer patients respond to androgen-deprivation therapy (ADT), the efficacy is widely variable. We investigated whether the host genetic variations in sex hormone pathway genes are associated with the efficacy of ADT. A cohort of 645 patients with advanced prostate ca...

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Bibliographic Details
Main Authors: Chia-Cheng Yu, Shu-Pin Huang, Yung-Chin Lee, Chao-Yuan Huang, Chia-Chu Liu, Tzyh-Chyuan Hour, Chun-Nung Huang, Bang-Jau You, Ta-Yuan Chang, Chun-Hsiung Huang, Bo-Ying Bao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3554749?pdf=render

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