Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy

Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy

Summary: Glioblastoma (GBM) metabolism has traditionally been characterized by a primary dependence on aerobic glycolysis, prompting the use of the ketogenic diet (KD) as a potential therapy. In this study we evaluated the effectiveness of the KD in GBM and assessed the role of fatty acid oxidation...

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Egile Nagusiak: Jantzen Sperry, Michael C. Condro, Lea Guo, Daniel Braas, Nathan Vanderveer-Harris, Kristen K.O. Kim, Whitney B. Pope, Ajit S. Divakaruni, Albert Lai, Heather Christofk, Maria G. Castro, Pedro R. Lowenstein, Janel E. Le Belle, Harley I. Kornblum
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Elsevier 2020-09-01
Saila:iScience
Gaiak:
Pathophysiology
Cancer
Diet
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2589004220306453

Internet

http://www.sciencedirect.com/science/article/pii/S2589004220306453

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