Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy

Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy

Summary: Glioblastoma (GBM) metabolism has traditionally been characterized by a primary dependence on aerobic glycolysis, prompting the use of the ketogenic diet (KD) as a potential therapy. In this study we evaluated the effectiveness of the KD in GBM and assessed the role of fatty acid oxidation...

Full description

Bibliographic Details
Main Authors: Jantzen Sperry, Michael C. Condro, Lea Guo, Daniel Braas, Nathan Vanderveer-Harris, Kristen K.O. Kim, Whitney B. Pope, Ajit S. Divakaruni, Albert Lai, Heather Christofk, Maria G. Castro, Pedro R. Lowenstein, Janel E. Le Belle, Harley I. Kornblum
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Pathophysiology
Cancer
Diet
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220306453

Similar Items

Similar Items