Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals

Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals

Summary: Chromosome segregation in mammals relies on the maturation of a thick bundle of kinetochore-attached microtubules known as k-fiber. How k-fibers mature from initial kinetochore microtubule attachments remains a fundamental question. By combining molecular perturbations and phenotypic analys...

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Bibliographic Details
Main Authors: Ana C. Almeida, Joana Soares-de-Oliveira, Danica Drpic, Liam P. Cheeseman, Joana Damas, Harris A. Lewin, Denis M. Larkin, Paulo Aguiar, António J. Pereira, Helder Maiato
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Cell Reports
Subjects:
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722003588

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