Application of the thrombin generation assay in patients with antiphospholipid syndrome: A systematic review of the literature

Application of the thrombin generation assay in patients with antiphospholipid syndrome: A systematic review of the literature

BackgroundThe antiphospholipid syndrome (APS) is classified by the presence of antiphospholipid antibodies (aPL) and thrombotic and/or adverse obstetric outcomes. The diagnosis and risk assessment of APS is challenging. This systematic review investigated if the thrombin generation (TG) assay could...

Full description

Bibliographic Details
Main Authors:	Rachel Gehlen, Arne Vandevelde, Bas de Laat, Katrien M. J. Devreese
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Cardiovascular Medicine
Subjects:	anitphospholipid antibodies antiphospholid syndrome pregnancy outcome thrombin generation thrombosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2023.1075121/full

Similar Items

Semi-automated thrombin dynamics applying the ST Genesia thrombin generation assay
by: Audrey Carlo, et al.
Published: (2022-07-01)

Laboratory Diagnosis of Antiphospholipid Syndrome: Insights and Hindrances
by: Arne Vandevelde, et al.
Published: (2022-04-01)

Long Term Follow up of Patients With Primary Obstetric Antiphospholipid Syndrome
by: Stanley Niznik, et al.
Published: (2022-04-01)

Influence of anticardiolipin and anti‐β2 glycoprotein I antibody cutoff values on antiphospholipid syndrome classification
by: Laura Vanoverschelde, et al.
Published: (2019-07-01)

Reference values for thrombin dynamics in platelet rich plasma
by: Qiuting Yan, et al.
Published: (2021-02-01)

Editorial: Advances in thrombin generation
by: Romy de Laat-Kremers, et al.
Published: (2023-03-01)

Patients With Multiple Myeloma Have a Disbalanced Whole Blood Thrombin Generation Profile
by: Li Li, et al.
Published: (2022-06-01)

Coagulation parameters predict COVID-19-related thrombosis in a neural network with a positive predictive value of 98%
by: Romy de Laat-Kremers, et al.
Published: (2022-09-01)

Comparison of Effects of Anti-thrombin Aptamers HD1 and HD22 on Aggregation of Human Platelets, Thrombin Generation, Fibrin Formation, and Thrombus Formation Under Flow Conditions
by: Katarzyna Derszniak, et al.
Published: (2019-02-01)

Assessing the individual roles of FII, FV, and FX activity in the thrombin generation process
by: Cuicui Bai, et al.
Published: (2022-09-01)

Thrombin generation assays to personalize treatment in bleeding and thrombotic diseases
by: Lars L. F. G. Valke, et al.
Published: (2022-11-01)

VWF, Platelets and the Antiphospholipid Syndrome
by: Shengshi Huang, et al.
Published: (2021-04-01)

Abacavir use is associated with increased prothrombin conversion
by: Qiuting Yan, et al.
Published: (2023-04-01)

Antiphospholipid Antibodies to Domain I of Beta-2-Glycoprotein I Show Different Subclass Predominance in Comparison to Antibodies to Whole Beta-2-glycoprotein I
by: Thomas McDonnell, et al.
Published: (2018-09-01)

A Hypoxic Environment Attenuates Exercise-Induced Procoagulant Changes Due to Decreased Platelet Activation
by: Cécile H. Kicken, et al.
Published: (2019-07-01)

Increased Clot Formation in the Absence of Increased Thrombin Generation in Patients with Peripheral Arterial Disease: A Case–Control Study
by: Marie-Claire F. Kleinegris, et al.
Published: (2017-04-01)

Role of antiphospholipid antibodies in the diagnosis of antiphospholipid syndrome
by: Katrien M.J. Devreese, et al.
Published: (2021-01-01)

Increased BMI and Blood Lipids Are Associated With a Hypercoagulable State in the Moli-sani Cohort
by: Romy de Laat-Kremers, et al.
Published: (2022-06-01)

Determining Thrombogenicity: Using a Modified Thrombin Generation Assay to Detect the Level of Thrombotic Event Risk in Lupus Anticoagulant-Positive Patients
by: Pavla Bradáčová, et al.
Published: (2023-12-01)

Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood
by: Sandra Konrath, et al.
Published: (2022-11-01)

Relationships between coagulation factors and thrombin generation in a general population with arterial and venous disease background
by: Pauline C. S. van Paridon, et al.
Published: (2022-06-01)

Thrombin generation by calibrated automated thrombography in goat plasma: Optimization of an assay
by: Elisa D'Alessandro, et al.
Published: (2021-12-01)

Hypercoagulability Evaluation in Antiphospholipid Syndrome without Anticoagulation Treatment with Thrombin Generation Assay: A Preliminary Study
by: Paul Billoir, et al.
Published: (2021-06-01)

D‐dimer, thrombin generation, and risk of a first venous thrombosis in the elderly
by: Huijie Wang, et al.
Published: (2021-07-01)

Thrombin generation assays for global evaluation of the hemostatic system: perspectives and limitations
by: Rita Carolina Figueiredo Duarte, et al.

Thrombin Generation and Cancer: Contributors and Consequences
by: Caroline J. Reddel, et al.
Published: (2019-01-01)

A simple activity assay for thrombin and hirudin /
by: 350239 Dang, Q. D., et al.

Targeting Platelet Thrombin Receptor Signaling to Prevent Thrombosis
by: Susan S. Smyth, et al.
Published: (2013-08-01)

Thrombin–Fibrinogen In Vitro Flow Model of Thrombus Growth in Cerebral Aneurysms
by: Malebogo N. Ngoepe, et al.
Published: (2021-04-01)

MicroRNA-126 is a regulator of platelet-supported thrombin generation
by: Veronika Zapilko, et al.
Published: (2020-08-01)

New High-Affinity Thrombin Aptamers for Advancing Coagulation Therapy: Balancing Thrombin Inhibition for Clot Prevention and Effective Bleeding Management with Antidote
by: Mohamad Ammar Ayass, et al.
Published: (2023-09-01)

Evaluation of thrombin generation in classical Philadelphianegative myeloproliferative neoplasms / Evaluarea generării trombinei în neoplasmele mieloproliferative Philadelphia- negative
by: Olteanu Ariela Ligia, et al.
Published: (2016-09-01)

Thrombin Generation and Atherothrombosis: What Does the Evidence Indicate?
by: Hugo ten Cate, et al.
Published: (2016-08-01)

Thrombin–Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis
by: Anne-Marije Hulshof, et al.
Published: (2021-03-01)

Comprehensive Analysis of the Role of Fibrinogen and Thrombin in Clot Formation and Structure for Plasma and Purified Fibrinogen
by: Rebecca A. Risman, et al.
Published: (2024-02-01)

Calibrated Automated Thrombinography (CAT), a Tool to Identify Patients at Risk of Bleeding during Anticoagulant Therapy: A Systematic Review
by: Suzanne Zwaveling, et al.
Published: (2018-07-01)

Coagulation challenges in pregnancy: from thrombophilia involvement and management to the utility of thrombin generation monitoring
by: R. Mihăilă
Published: (2020-12-01)

Thrombin generation as a predictor of outcomes in patients with non-traumatic intracerebral hemorrhage
by: Linda Lóczi, et al.
Published: (2022-08-01)

ST Genesia reference values of 117 healthy donors measured with STG‐BleedScreen, STG‐DrugScreen and STG‐ThromboScreen reagents
by: Marisa Ninivaggi, et al.
Published: (2021-01-01)

The clinical usefulness of measuring thrombin generation
by: Coenraad H. Hemker
Published: (2023-03-01)