Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations
This case–control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated va...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2023-01-01
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| Series: | Antimicrobial Stewardship & Healthcare Epidemiology |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2732494X23001638/type/journal_article |
| _version_ | 1797835052123422720 |
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| author | Alexandra G. Mills Amy C. Dupper Kieran I. Chacko Bremy Alburquerque Devika Nadkarni Ana Berbel Caban Lindsey Fox Melissa R. Gitman Ajay Obla Harm van Bakel Deena R. Altman |
| author_facet | Alexandra G. Mills Amy C. Dupper Kieran I. Chacko Bremy Alburquerque Devika Nadkarni Ana Berbel Caban Lindsey Fox Melissa R. Gitman Ajay Obla Harm van Bakel Deena R. Altman |
| author_sort | Alexandra G. Mills |
| collection | DOAJ |
| description | This case–control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated vancomycin MIC. Elevated vancomycin MIC was associated with baseline hemodialysis, prior MRSA colonization, and metastatic infection. |
| first_indexed | 2024-04-09T14:48:10Z |
| format | Article |
| id | doaj.art-c411cfe869ef410f820489fb24a5913c |
| institution | Directory Open Access Journal |
| issn | 2732-494X |
| language | English |
| last_indexed | 2024-04-09T14:48:10Z |
| publishDate | 2023-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Antimicrobial Stewardship & Healthcare Epidemiology |
| spelling | doaj.art-c411cfe869ef410f820489fb24a5913c2023-05-02T10:55:42ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2023-01-01310.1017/ash.2023.163Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrationsAlexandra G. Mills0https://orcid.org/0000-0002-4473-8096Amy C. Dupper1Kieran I. Chacko2https://orcid.org/0000-0002-1024-4063Bremy Alburquerque3https://orcid.org/0000-0002-9115-8318Devika Nadkarni4Ana Berbel Caban5https://orcid.org/0000-0002-1629-2939Lindsey Fox6Melissa R. Gitman7https://orcid.org/0000-0002-6960-0763Ajay Obla8https://orcid.org/0000-0003-4713-3284Harm van Bakel9https://orcid.org/0000-0002-1376-6916Deena R. Altman10https://orcid.org/0000-0003-1948-3834Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New YorkDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New YorkDepartment of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, New YorkDepartment of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, New YorkDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New YorkDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New YorkDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New YorkDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New YorkDepartment of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, New YorkDepartment of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, New York Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, New YorkDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, New York, New YorkThis case–control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated vancomycin MIC. Elevated vancomycin MIC was associated with baseline hemodialysis, prior MRSA colonization, and metastatic infection.https://www.cambridge.org/core/product/identifier/S2732494X23001638/type/journal_article |
| spellingShingle | Alexandra G. Mills Amy C. Dupper Kieran I. Chacko Bremy Alburquerque Devika Nadkarni Ana Berbel Caban Lindsey Fox Melissa R. Gitman Ajay Obla Harm van Bakel Deena R. Altman Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations Antimicrobial Stewardship & Healthcare Epidemiology |
| title | Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations |
| title_full | Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations |
| title_fullStr | Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations |
| title_full_unstemmed | Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations |
| title_short | Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations |
| title_sort | methicillin resistant staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations |
| url | https://www.cambridge.org/core/product/identifier/S2732494X23001638/type/journal_article |
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