Protein Dynamics in Cytosolic DNA-Sensing Antiviral Innate Immune Signaling Pathways

Protein Dynamics in Cytosolic DNA-Sensing Antiviral Innate Immune Signaling Pathways

Antiviral innate immunity works as the first line of host defense against viral infection. Pattern recognition receptors (PRRs) and adaptor proteins involved in the innate immune signaling pathways play critical roles in controlling viral infections via the induction of type I interferon and its dow...

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Bibliographic Details
Main Author: Chunfu Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
protein dynamics
protein trafficking
conformational change
DNA sensing signaling
innate immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01255/full

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