Primary splenic diffuse large B-cell lymphoma: a case report
Primary splenic lymphoma (PSL) is a rare disease and an improbable cause of splenomegaly or splenic nodules. On the contrary, splenic secondary involvement as part of an advanced lymphoproliferative disorder is more common. The authors present the case of a 49-year-old woman with a primary splenic d...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2023-06-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/3932 |
| _version_ | 1797782644979662848 |
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| author | Nuno Maia Neves Ana Pestana Lopes Susana Carvalho Coelho Anabela Raimundo Maria Manuela Mafra Alexandra Bayão Horta |
| author_facet | Nuno Maia Neves Ana Pestana Lopes Susana Carvalho Coelho Anabela Raimundo Maria Manuela Mafra Alexandra Bayão Horta |
| author_sort | Nuno Maia Neves |
| collection | DOAJ |
| description | Primary splenic lymphoma (PSL) is a rare disease and an improbable cause of splenomegaly or splenic nodules. On the contrary, splenic secondary involvement as part of an advanced lymphoproliferative disorder is more common.
The authors present the case of a 49-year-old woman with a primary splenic diffuse large B-cell lymphoma (PS-DLBCL), in which the absence of other organs’ involvement determined an ultrasound-guided biopsy of the spleen to achieve a definitive diagnosis.
With this case the authors intend to emphasise the extensive differential diagnosis of splenomegaly, splenic nodules or infiltrates, the usefulness of splenic biopsy in establishing the diagnosis and recall a rare disease, with non-specific presenting symptoms, in which the diagnostic workup is challenging. |
| first_indexed | 2024-03-13T00:13:53Z |
| format | Article |
| id | doaj.art-c41443a3ea7646338e1072060c8c5035 |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-03-13T00:13:53Z |
| publishDate | 2023-06-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-c41443a3ea7646338e1072060c8c50352023-07-12T07:29:01ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942023-06-0110.12890/2023_0039323467Primary splenic diffuse large B-cell lymphoma: a case reportNuno Maia Neves0Ana Pestana Lopes1Susana Carvalho Coelho2Anabela Raimundo3Maria Manuela Mafra4Alexandra Bayão Horta5Internal Medicine Department, Hospital da Luz Lisboa, Lisbon, PortugalAnatomical Pathology Department, Hospital da Luz Lisboa, Lisbon, PortugalInternal Medicine Department, Hospital da Luz Lisboa, Lisbon, PortugalInternal Medicine Department, Hospital da Luz Lisboa, Lisbon, PortugalAnatomical Pathology Department, Hospital da Luz Lisboa, Lisbon, PortugalInternal Medicine Department, Hospital da Luz Lisboa, Lisbon, PortugalPrimary splenic lymphoma (PSL) is a rare disease and an improbable cause of splenomegaly or splenic nodules. On the contrary, splenic secondary involvement as part of an advanced lymphoproliferative disorder is more common. The authors present the case of a 49-year-old woman with a primary splenic diffuse large B-cell lymphoma (PS-DLBCL), in which the absence of other organs’ involvement determined an ultrasound-guided biopsy of the spleen to achieve a definitive diagnosis. With this case the authors intend to emphasise the extensive differential diagnosis of splenomegaly, splenic nodules or infiltrates, the usefulness of splenic biopsy in establishing the diagnosis and recall a rare disease, with non-specific presenting symptoms, in which the diagnostic workup is challenging.https://www.ejcrim.com/index.php/EJCRIM/article/view/3932primary splenic lymphomadiffuse large b-cell lymphomanon-hodgkin lymphomasplenomegalysplenic nodules |
| spellingShingle | Nuno Maia Neves Ana Pestana Lopes Susana Carvalho Coelho Anabela Raimundo Maria Manuela Mafra Alexandra Bayão Horta Primary splenic diffuse large B-cell lymphoma: a case report European Journal of Case Reports in Internal Medicine primary splenic lymphoma diffuse large b-cell lymphoma non-hodgkin lymphoma splenomegaly splenic nodules |
| title | Primary splenic diffuse large B-cell lymphoma: a case report |
| title_full | Primary splenic diffuse large B-cell lymphoma: a case report |
| title_fullStr | Primary splenic diffuse large B-cell lymphoma: a case report |
| title_full_unstemmed | Primary splenic diffuse large B-cell lymphoma: a case report |
| title_short | Primary splenic diffuse large B-cell lymphoma: a case report |
| title_sort | primary splenic diffuse large b cell lymphoma a case report |
| topic | primary splenic lymphoma diffuse large b-cell lymphoma non-hodgkin lymphoma splenomegaly splenic nodules |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/3932 |
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