Human Cystathionine γ-Lyase Is Inhibited by <i>s</i>-Nitrosation: A New Crosstalk Mechanism between NO and H<sub>2</sub>S

Human Cystathionine γ-Lyase Is Inhibited by <i>s</i>-Nitrosation: A New Crosstalk Mechanism between NO and H<sub>2</sub>S

The ‘gasotransmitters’ hydrogen sulfide (H<sub>2</sub>S), nitric oxide (NO), and carbon monoxide (CO) act as second messengers in human physiology, mediating signal transduction via interaction with or chemical modification of protein targets, thereby regulating processes such as neurotr...

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Bibliographic Details
Main Authors: Dalila G. F. Fernandes, João Nunes, Catarina S. Tomé, Karim Zuhra, João M. F. Costa, Alexandra M. M. Antunes, Alessandro Giuffrè, João B. Vicente
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antioxidants
Subjects:
hydrogen sulfide
<i>s</i>-nitrosoglutathione
gasotransmitters
cystathionine γ-lyase
signaling
crosstalk
Online Access:https://www.mdpi.com/2076-3921/10/9/1391

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