In Vivo Measurement of Neurochemical Abnormalities in the Hippocampus in a Rat Model of Cuprizone-Induced Demyelination

In Vivo Measurement of Neurochemical Abnormalities in the Hippocampus in a Rat Model of Cuprizone-Induced Demyelination

This study quantitatively measured the changes in metabolites in the hippocampal lesions of a rat model of cuprizone-induced demyelination as detected using in vivo 7 T proton magnetic resonance spectroscopy. Nineteen Sprague Dawley rats were randomly divided into two groups and fed a normal chow di...

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Bibliographic Details
Main Authors: Do-Wan Lee, Jae-Im Kwon, Chul-Woong Woo, Hwon Heo, Kyung Won Kim, Dong-Cheol Woo, Jeong Kon Kim, Dong-Hoon Lee
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Diagnostics
Subjects:
rat brain
demyelination
hippocampus
metabolites
multiple sclerosis
Online Access:https://www.mdpi.com/2075-4418/11/1/45

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