Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome

Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome

Abstract Background Numerous case studies have reported spontaneous regression of recognized metastases following primary tumor excision, but underlying mechanisms are elusive. Here, we present a model of regression and latency of metastases following primary tumor excision and identify potential un...

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Bibliographic Details
Main Authors: Lee Shaashua, Anabel Eckerling, Boaz Israeli, Gali Yanovich, Ella Rosenne, Suzana Fichman-Horn, Ido Ben Zvi, Liat Sorski, Rita Haldar, Ronit Satchi-Fainaro, Tamar Geiger, Erica K. Sloan, Shamgar Ben-Eliyahu
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Biology
Subjects:
Metastatic regression
Breast cancer
Surgery
Removal of primary tumor
Cancer secretome
Online Access:http://link.springer.com/article/10.1186/s12915-020-00893-2

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