Identification of a Conserved Prophenoloxidase Activation Pathway in Cotton Bollworm Helicoverpa armigera

Identification of a Conserved Prophenoloxidase Activation Pathway in Cotton Bollworm Helicoverpa armigera

Melanization is a prominent insect humoral response for encapsulation of and killing invading pathogens. It is mediated by a protease cascade composed of a modular serine protease (SP), and clip domain SPs (cSPs), which converts prophenoloxidase (PPO) into active phenoloxidase (PO). To date, melaniz...

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Bibliographic Details
Main Authors: Qianran Wang, Mengyi Yin, Chuanfei Yuan, Xijia Liu, Zhihong Hu, Zhen Zou, Manli Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
melanization
prophenoloxidase
serine protease
baculovirus
Helicoverpa armigera
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00785/full

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