Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

Depression is a common comorbid condition in Parkinson’s disease (PD). Patients with depression have a two-fold increased risk to develop PD. Further, depression symptoms often precede motor symptoms in PD and are frequent at all stages of the disease. However, the influence of a depressive state on...

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Bibliographic Details
Main Authors: Nicoletta Schintu, Xiaoqun Zhang, Nikolas Stroth, Aleksander A. Mathé, Per E. Andrén, Per Svenningsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
flinders sensitive line
Parkinson’s disease
L-DOPA
dyskinesia
tremor
tamalin
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00304/full

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