Primary hip arthroplasty for the treatment of alkaptonuric hip arthritis: 3- to 24-year follow-ups

Abstract Background The objective of this study is to share our experience in total hip replacement for the treatment of ochronotic hip arthritis, in particular to report how to establish the diagnosis and some tips to limit complications. Method A cohort comprised of 10 patients (12 hips) with alka...

Full description

Bibliographic Details
Main Authors: Javahir A. Pachore, Vikram Indrajit Shah, Sachin Upadhyay, Kalpesh Shah, Ashish Sheth, Amish Kshatriya
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Arthroplasty
Subjects:
Online Access:http://link.springer.com/article/10.1186/s42836-019-0010-8
_version_ 1811324701112270848
author Javahir A. Pachore
Vikram Indrajit Shah
Sachin Upadhyay
Kalpesh Shah
Ashish Sheth
Amish Kshatriya
author_facet Javahir A. Pachore
Vikram Indrajit Shah
Sachin Upadhyay
Kalpesh Shah
Ashish Sheth
Amish Kshatriya
author_sort Javahir A. Pachore
collection DOAJ
description Abstract Background The objective of this study is to share our experience in total hip replacement for the treatment of ochronotic hip arthritis, in particular to report how to establish the diagnosis and some tips to limit complications. Method A cohort comprised of 10 patients (12 hips) with alkaptonuric hip arthritis. There were six men and four women with the mean age of 62.80 ± 7.57 years. All patients had a stiff spine, grossly restricted movements of hip joints, and severely limited daily routine activities. Total hip replacement was performed in all patients. The patients were evaluated at 6, 12, and 24 months after surgery, as well as every 4 years thereafter. Harris hip score was used to assess the functional outcome. The level of significance was set at p < 0.05. Results The mean follow-up lasted 16.70 ± 6.82 years (3 to 24 years). At the final available follow-up, nine patients returned to work, ambulate without an orthosis, and achieve complete pain relief. Harris hip score was improved from poor to excellent. One patient died 16 years after surgery due to breast cancer. No complication relating to prosthetic failures was detected. Conclusion Total hip replacement gives long-term satisfactory results in patients with alkaptonuric hip arthritis, resulting in comparable function of the hips in patients who undergo primary osteoarthrosis.
first_indexed 2024-04-13T14:19:04Z
format Article
id doaj.art-c42c94ec8cb04cd69762af29f8781eff
institution Directory Open Access Journal
issn 2524-7948
language English
last_indexed 2024-04-13T14:19:04Z
publishDate 2019-10-01
publisher BMC
record_format Article
series Arthroplasty
spelling doaj.art-c42c94ec8cb04cd69762af29f8781eff2022-12-22T02:43:33ZengBMCArthroplasty2524-79482019-10-01111910.1186/s42836-019-0010-8Primary hip arthroplasty for the treatment of alkaptonuric hip arthritis: 3- to 24-year follow-upsJavahir A. Pachore0Vikram Indrajit Shah1Sachin Upadhyay2Kalpesh Shah3Ashish Sheth4Amish Kshatriya5Department of Hip Arthroplasty, Shalby HospitalsDepartment of Hip Arthroplasty, Shalby HospitalsDepartment of Orthopaedics, NSCB Medical CollegeDepartment of Knee and Hip Arthroplasty, Shalby HospitalsDepartment of Knee and Hip Arthroplasty, Shalby HospitalsDepartment of Knee and Hip Arthroplasty, Shalby HospitalsAbstract Background The objective of this study is to share our experience in total hip replacement for the treatment of ochronotic hip arthritis, in particular to report how to establish the diagnosis and some tips to limit complications. Method A cohort comprised of 10 patients (12 hips) with alkaptonuric hip arthritis. There were six men and four women with the mean age of 62.80 ± 7.57 years. All patients had a stiff spine, grossly restricted movements of hip joints, and severely limited daily routine activities. Total hip replacement was performed in all patients. The patients were evaluated at 6, 12, and 24 months after surgery, as well as every 4 years thereafter. Harris hip score was used to assess the functional outcome. The level of significance was set at p < 0.05. Results The mean follow-up lasted 16.70 ± 6.82 years (3 to 24 years). At the final available follow-up, nine patients returned to work, ambulate without an orthosis, and achieve complete pain relief. Harris hip score was improved from poor to excellent. One patient died 16 years after surgery due to breast cancer. No complication relating to prosthetic failures was detected. Conclusion Total hip replacement gives long-term satisfactory results in patients with alkaptonuric hip arthritis, resulting in comparable function of the hips in patients who undergo primary osteoarthrosis.http://link.springer.com/article/10.1186/s42836-019-0010-8Total hip replacementAlkaptonuric arthritisOchronosisHarris hip score
spellingShingle Javahir A. Pachore
Vikram Indrajit Shah
Sachin Upadhyay
Kalpesh Shah
Ashish Sheth
Amish Kshatriya
Primary hip arthroplasty for the treatment of alkaptonuric hip arthritis: 3- to 24-year follow-ups
Arthroplasty
Total hip replacement
Alkaptonuric arthritis
Ochronosis
Harris hip score
title Primary hip arthroplasty for the treatment of alkaptonuric hip arthritis: 3- to 24-year follow-ups
title_full Primary hip arthroplasty for the treatment of alkaptonuric hip arthritis: 3- to 24-year follow-ups
title_fullStr Primary hip arthroplasty for the treatment of alkaptonuric hip arthritis: 3- to 24-year follow-ups
title_full_unstemmed Primary hip arthroplasty for the treatment of alkaptonuric hip arthritis: 3- to 24-year follow-ups
title_short Primary hip arthroplasty for the treatment of alkaptonuric hip arthritis: 3- to 24-year follow-ups
title_sort primary hip arthroplasty for the treatment of alkaptonuric hip arthritis 3 to 24 year follow ups
topic Total hip replacement
Alkaptonuric arthritis
Ochronosis
Harris hip score
url http://link.springer.com/article/10.1186/s42836-019-0010-8
work_keys_str_mv AT javahirapachore primaryhiparthroplastyforthetreatmentofalkaptonurichiparthritis3to24yearfollowups
AT vikramindrajitshah primaryhiparthroplastyforthetreatmentofalkaptonurichiparthritis3to24yearfollowups
AT sachinupadhyay primaryhiparthroplastyforthetreatmentofalkaptonurichiparthritis3to24yearfollowups
AT kalpeshshah primaryhiparthroplastyforthetreatmentofalkaptonurichiparthritis3to24yearfollowups
AT ashishsheth primaryhiparthroplastyforthetreatmentofalkaptonurichiparthritis3to24yearfollowups
AT amishkshatriya primaryhiparthroplastyforthetreatmentofalkaptonurichiparthritis3to24yearfollowups