Frailty in kidney transplant candidates and recipients: pathogenesis and intervention strategies

Abstract. With the rapid aging of the global population posing a serious problem, frailty, a non-specific state that reflects physiological senescence rather than aging in time, has become more widely addressed by researchers in various medical fields. A high prevalence of frailty is found among kid...

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Những tác giả chính: Huawei Cao, Jiandong Zhang, Zejia Sun, Jiyue Wu, Changzhen Hao, Wei Wang, Yanjie Yin
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Wolters Kluwer 2023-05-01
Loạt:Chinese Medical Journal
Truy cập trực tuyến:http://journals.lww.com/10.1097/CM9.0000000000002312
Miêu tả
Tóm tắt:Abstract. With the rapid aging of the global population posing a serious problem, frailty, a non-specific state that reflects physiological senescence rather than aging in time, has become more widely addressed by researchers in various medical fields. A high prevalence of frailty is found among kidney transplant (KT) candidates and recipients. Therefore, their frailty has become a research hotspot in the field of transplantation. However, current studies mainly focus on the cross-sectional survey of the incidence of frailty among KT candidates and recipients and the relationship between frailty and transplantation. Research on the pathogenesis and intervention is scattered, and relevant review literature is scarce. Exploring the pathogenesis of frailty in KT candidates and recipients and determining effective intervention measures may reduce waiting list mortality and improve the long-term quality of life of KT recipients. Therefore, this review explains the pathogenesis and intervention measures for frailty in KT candidates and recipients to provide a reference for the formulation of effective intervention strategies.
số ISSN:0366-6999
2542-5641