A study of effect of hemodialysis on macular thickness in patients with end-stage renal disease
PURPOSE: The purpose was to study the effect of hemodialysis (HD) on macular thickness in patients with diabetic retinopathy (DR) and end-stage renal disease. MATERIALS AND METHODS: In this prospective observational study, patients undergoing HD for diabetic nephropathy were recruited. None of the p...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Taiwan Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.e-tjo.org/article.asp?issn=2211-5056;year=2021;volume=11;issue=4;spage=367;epage=371;aulast=Suryakanth |
| _version_ | 1818968256929595392 |
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| author | Shwetha Suryakanth H N Ravi Shankar Mallikarjun M Heralgi Pradeep Sagar V Kavitha S Mahesha N Suresh Babu Pradeep Tekade |
| author_facet | Shwetha Suryakanth H N Ravi Shankar Mallikarjun M Heralgi Pradeep Sagar V Kavitha S Mahesha N Suresh Babu Pradeep Tekade |
| author_sort | Shwetha Suryakanth |
| collection | DOAJ |
| description | PURPOSE: The purpose was to study the effect of hemodialysis (HD) on macular thickness in patients with diabetic retinopathy (DR) and end-stage renal disease.
MATERIALS AND METHODS: In this prospective observational study, patients undergoing HD for diabetic nephropathy were recruited. None of the patients received treatment for DR per se during the study duration. Patients underwent ocular examination and optical coherence tomography before HD and were followed up on day 3 and day 30. At each visit, central subfield macular thickness (CSMT) and total macular volume (TMV) were measured and compared with baseline values using analysis of variance and post hoc test (Wilcoxon's matched-pairs signed-rank test).
RESULTS: Thirty-one eyes of 19 patients were recruited in the study. The mean CSMT decreased from baseline value of 278.93 ± 45.01 μ to 239.81 ± 40.54 μ at the end of 30 days (P < 0.005). The mean TMV decreased from baseline value of 8.14 ± 0.68 mm3 to 7.80 ± 0.63 mm3 on day 30 (P < 0.005).
CONCLUSION: There was a statistically significant reduction in CSMT and TMV after HD at 30 days as compared to baseline values. HD alone results in reduction of macular thickness over short term. |
| first_indexed | 2024-12-20T14:01:48Z |
| format | Article |
| id | doaj.art-c433712e11e94befb0df2c2c4acedd3a |
| institution | Directory Open Access Journal |
| issn | 2211-5056 2211-5072 |
| language | English |
| last_indexed | 2024-12-20T14:01:48Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Taiwan Journal of Ophthalmology |
| spelling | doaj.art-c433712e11e94befb0df2c2c4acedd3a2022-12-21T19:38:21ZengWolters Kluwer Medknow PublicationsTaiwan Journal of Ophthalmology2211-50562211-50722021-01-0111436737110.4103/tjo.tjo_86_20A study of effect of hemodialysis on macular thickness in patients with end-stage renal diseaseShwetha SuryakanthH N Ravi ShankarMallikarjun M HeralgiPradeep SagarV KavithaS MaheshaN Suresh BabuPradeep TekadePURPOSE: The purpose was to study the effect of hemodialysis (HD) on macular thickness in patients with diabetic retinopathy (DR) and end-stage renal disease. MATERIALS AND METHODS: In this prospective observational study, patients undergoing HD for diabetic nephropathy were recruited. None of the patients received treatment for DR per se during the study duration. Patients underwent ocular examination and optical coherence tomography before HD and were followed up on day 3 and day 30. At each visit, central subfield macular thickness (CSMT) and total macular volume (TMV) were measured and compared with baseline values using analysis of variance and post hoc test (Wilcoxon's matched-pairs signed-rank test). RESULTS: Thirty-one eyes of 19 patients were recruited in the study. The mean CSMT decreased from baseline value of 278.93 ± 45.01 μ to 239.81 ± 40.54 μ at the end of 30 days (P < 0.005). The mean TMV decreased from baseline value of 8.14 ± 0.68 mm3 to 7.80 ± 0.63 mm3 on day 30 (P < 0.005). CONCLUSION: There was a statistically significant reduction in CSMT and TMV after HD at 30 days as compared to baseline values. HD alone results in reduction of macular thickness over short term.http://www.e-tjo.org/article.asp?issn=2211-5056;year=2021;volume=11;issue=4;spage=367;epage=371;aulast=Suryakanthdiabetic nephropathydiabetic retinopathyhemodialysismacular edema |
| spellingShingle | Shwetha Suryakanth H N Ravi Shankar Mallikarjun M Heralgi Pradeep Sagar V Kavitha S Mahesha N Suresh Babu Pradeep Tekade A study of effect of hemodialysis on macular thickness in patients with end-stage renal disease Taiwan Journal of Ophthalmology diabetic nephropathy diabetic retinopathy hemodialysis macular edema |
| title | A study of effect of hemodialysis on macular thickness in patients with end-stage renal disease |
| title_full | A study of effect of hemodialysis on macular thickness in patients with end-stage renal disease |
| title_fullStr | A study of effect of hemodialysis on macular thickness in patients with end-stage renal disease |
| title_full_unstemmed | A study of effect of hemodialysis on macular thickness in patients with end-stage renal disease |
| title_short | A study of effect of hemodialysis on macular thickness in patients with end-stage renal disease |
| title_sort | study of effect of hemodialysis on macular thickness in patients with end stage renal disease |
| topic | diabetic nephropathy diabetic retinopathy hemodialysis macular edema |
| url | http://www.e-tjo.org/article.asp?issn=2211-5056;year=2021;volume=11;issue=4;spage=367;epage=371;aulast=Suryakanth |
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