The Role of Coronary CT Angiography in the Evaluation of Dual Left Anterior Descending Artery Prevalence and Subtypes: A Retrospective Multicenter Study
Background: The aim of this multicenter study was to evaluate the prevalence and features of dual left anterior descending artery (LAD) subtypes using coronary CT angiography (CCTA). Methods: A retrospective multicenter analysis of 2083 CCTA from December 2020 to November 2022 was conducted to searc...
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MDPI AG
2023-07-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/13/7/1127 |
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| author | Nicola Maggialetti Sara Greco Giovanni Lorusso Cristiana Mileti Gabriella Sfregola Maria Chiara Brunese Marcello Zappia Maria Paola Belfiore Pasquale Sullo Alfonso Reginelli Nicola Maria Lucarelli Arnaldo Scardapane |
| author_facet | Nicola Maggialetti Sara Greco Giovanni Lorusso Cristiana Mileti Gabriella Sfregola Maria Chiara Brunese Marcello Zappia Maria Paola Belfiore Pasquale Sullo Alfonso Reginelli Nicola Maria Lucarelli Arnaldo Scardapane |
| author_sort | Nicola Maggialetti |
| collection | DOAJ |
| description | Background: The aim of this multicenter study was to evaluate the prevalence and features of dual left anterior descending artery (LAD) subtypes using coronary CT angiography (CCTA). Methods: A retrospective multicenter analysis of 2083 CCTA from December 2020 to November 2022 was conducted to search for the presence and morphological features of dual LAD. The two classifications used were the updated classification of Spindola-Franco and the Jariwala classification. Statistical tests were conducted to evaluate the prevalence of dual LADs among sexes and its association with angina in patients without significant coronary stenoses and/or associated cardiac anomalies. Results: Dual LAD was observed in 124 (5.96%) patients analyzed. According to the Spindola-Franco revisited classification, type I dual LAD was the most common (71/124, 57.26%). According to the Jariwala classification, all cases were group I. In the general population, there was a higher prevalence of dual LAD among females (7.3% females vs. 5.1% males; <i>p</i> value: 0.04). No statistically significant difference was found in the prevalence of angina in the dual LAD population compared to the no dual LAD population (2.1% vs. 1.5%; <i>p</i> value: 0.10). Conclusions: The acknowledgment and reporting of LAD duplication is helpful for an optimal management of coronary patients with this condition. Dual LAD was more frequent in the female population, mainly not related with angina. Myocardial bridge was more frequent in the dual LAD population than in the no dual LAD population. |
| first_indexed | 2024-03-11T00:56:04Z |
| format | Article |
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| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-11T00:56:04Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-c437bb85a576442b942875e9e40d16af2023-11-18T20:04:01ZengMDPI AGJournal of Personalized Medicine2075-44262023-07-01137112710.3390/jpm13071127The Role of Coronary CT Angiography in the Evaluation of Dual Left Anterior Descending Artery Prevalence and Subtypes: A Retrospective Multicenter StudyNicola Maggialetti0Sara Greco1Giovanni Lorusso2Cristiana Mileti3Gabriella Sfregola4Maria Chiara Brunese5Marcello Zappia6Maria Paola Belfiore7Pasquale Sullo8Alfonso Reginelli9Nicola Maria Lucarelli10Arnaldo Scardapane11Interdisciplinary Department of Medicine, Section of Radiology and Radiation Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalyInterdisciplinary Department of Medicine, Section of Radiology and Radiation Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalyInterdisciplinary Department of Medicine, Section of Radiology and Radiation Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalyInterdisciplinary Department of Medicine, Section of Radiology and Radiation Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalyInterdisciplinary Department of Medicine, Section of Radiology and Radiation Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalyDiagnostic Imaging Section, Department of Medical and Surgical Sciences & Neurosciences, University of Molise, 86100 Campobasso, ItalyDepartment of Medicine and Health Science, University of Molise, 86100 Campobasso, ItalyDepartment of Precision Medicine, University of Campania “Luigi Vanvitelli”, 80123 Naples, ItalySant’Anna e San Sebastiano Hospital of Caserta, Radiology Division, 81100 Caserta, ItalyDepartment of Precision Medicine, University of Campania “Luigi Vanvitelli”, 80123 Naples, ItalyInterdisciplinary Department of Medicine, Section of Radiology and Radiation Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalyInterdisciplinary Department of Medicine, Section of Radiology and Radiation Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalyBackground: The aim of this multicenter study was to evaluate the prevalence and features of dual left anterior descending artery (LAD) subtypes using coronary CT angiography (CCTA). Methods: A retrospective multicenter analysis of 2083 CCTA from December 2020 to November 2022 was conducted to search for the presence and morphological features of dual LAD. The two classifications used were the updated classification of Spindola-Franco and the Jariwala classification. Statistical tests were conducted to evaluate the prevalence of dual LADs among sexes and its association with angina in patients without significant coronary stenoses and/or associated cardiac anomalies. Results: Dual LAD was observed in 124 (5.96%) patients analyzed. According to the Spindola-Franco revisited classification, type I dual LAD was the most common (71/124, 57.26%). According to the Jariwala classification, all cases were group I. In the general population, there was a higher prevalence of dual LAD among females (7.3% females vs. 5.1% males; <i>p</i> value: 0.04). No statistically significant difference was found in the prevalence of angina in the dual LAD population compared to the no dual LAD population (2.1% vs. 1.5%; <i>p</i> value: 0.10). Conclusions: The acknowledgment and reporting of LAD duplication is helpful for an optimal management of coronary patients with this condition. Dual LAD was more frequent in the female population, mainly not related with angina. Myocardial bridge was more frequent in the dual LAD population than in the no dual LAD population.https://www.mdpi.com/2075-4426/13/7/1127coronary computed tomography angiography (CCTA)coronary arterydual left anterior descending artery (LAD)myocardial bridgeangina |
| spellingShingle | Nicola Maggialetti Sara Greco Giovanni Lorusso Cristiana Mileti Gabriella Sfregola Maria Chiara Brunese Marcello Zappia Maria Paola Belfiore Pasquale Sullo Alfonso Reginelli Nicola Maria Lucarelli Arnaldo Scardapane The Role of Coronary CT Angiography in the Evaluation of Dual Left Anterior Descending Artery Prevalence and Subtypes: A Retrospective Multicenter Study Journal of Personalized Medicine coronary computed tomography angiography (CCTA) coronary artery dual left anterior descending artery (LAD) myocardial bridge angina |
| title | The Role of Coronary CT Angiography in the Evaluation of Dual Left Anterior Descending Artery Prevalence and Subtypes: A Retrospective Multicenter Study |
| title_full | The Role of Coronary CT Angiography in the Evaluation of Dual Left Anterior Descending Artery Prevalence and Subtypes: A Retrospective Multicenter Study |
| title_fullStr | The Role of Coronary CT Angiography in the Evaluation of Dual Left Anterior Descending Artery Prevalence and Subtypes: A Retrospective Multicenter Study |
| title_full_unstemmed | The Role of Coronary CT Angiography in the Evaluation of Dual Left Anterior Descending Artery Prevalence and Subtypes: A Retrospective Multicenter Study |
| title_short | The Role of Coronary CT Angiography in the Evaluation of Dual Left Anterior Descending Artery Prevalence and Subtypes: A Retrospective Multicenter Study |
| title_sort | role of coronary ct angiography in the evaluation of dual left anterior descending artery prevalence and subtypes a retrospective multicenter study |
| topic | coronary computed tomography angiography (CCTA) coronary artery dual left anterior descending artery (LAD) myocardial bridge angina |
| url | https://www.mdpi.com/2075-4426/13/7/1127 |
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