Pharmacogenomics of soft tissue sarcomas: New horizons to understand efficacy and toxicity

Pharmacogenomics of soft tissue sarcomas: New horizons to understand efficacy and toxicity

Clinical responses to anticancer therapies in advanced soft tissue sarcoma (STS) are unfortunately limited to a small subset of patients. Much of the inter-individual variability in treatment efficacy and risk of toxicities is as result of polymorphisms in genes encoding proteins involved in drug ph...

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Bibliographic Details
Main Authors: Elisabetta Gambale, Anna Boddi, Adriano Pasqui, Domenico Andrea Campanacci, Guido Scoccianti, Ilaria Palchetti, Andrea Bernini, Lorenzo Antonuzzo, Serena Pillozzi
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cancer Treatment and Research Communications
Subjects:
Soft tissue sarcoma
Cancer pharmacogenetic
Pharmacogenomics
Single-nucleotide polymorphisms
Toxicity
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2468294222000193

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http://www.sciencedirect.com/science/article/pii/S2468294222000193

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