Conformational Changes of the Receptor Binding Domain of SARS-CoV-2 Spike Protein and Prediction of a B-Cell Antigenic Epitope Using Structural Data

Conformational Changes of the Receptor Binding Domain of SARS-CoV-2 Spike Protein and Prediction of a B-Cell Antigenic Epitope Using Structural Data

COVID-19, the illness caused by the SARS-CoV-2 virus, is now a worldwide pandemic with mortality in hundreds of thousands as infections continue to increase. Containing the spread of this viral infection and decreasing the mortality rate is a major challenge. Identifying appropriate antigenic epitop...

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Bibliographic Details
Main Authors: Sangeeta Khare, Marli Azevedo, Pravin Parajuli, Kuppan Gokulan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Artificial Intelligence
Subjects:
spike protein
SARS–CoV−2
receptor binding domian
conformational epitope
viral infection
Online Access:https://www.frontiersin.org/articles/10.3389/frai.2021.630955/full

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