Structural neural connectivity of the vestibular nuclei in the human brain: a diffusion tensor imagingS study
Many animal studies have reported on the neural connectivity of the vestibular nuclei (VN). However, little is reported on the structural neural connectivity of the VN in the human brain. In this study, we attempted to investigate the structural neural connectivity of the VN in 37 healthy subjects u...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Neural Regeneration Research |
| Subjects: | |
| Online Access: | http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=4;spage=727;epage=730;aulast=Jang |
| _version_ | 1818015264603635712 |
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| author | Sung Ho Jang Mi Young Lee Sang Seok Yeo Hyeok Gyu Kwon |
| author_facet | Sung Ho Jang Mi Young Lee Sang Seok Yeo Hyeok Gyu Kwon |
| author_sort | Sung Ho Jang |
| collection | DOAJ |
| description | Many animal studies have reported on the neural connectivity of the vestibular nuclei (VN). However, little is reported on the structural neural connectivity of the VN in the human brain. In this study, we attempted to investigate the structural neural connectivity of the VN in 37 healthy subjects using diffusion tensor tractography. A seed region of interest was placed on the isolated VN using probabilistic diffusion tensor tractography. Connectivity was defined as the incidence of connection between the VN and each brain region. The VN showed 100% connectivity with the cerebellum, thalamus, oculomotor nucleus, trochlear nucleus, abducens nucleus, and reticular formation, irrespective of thresholds. At the threshold of 5 streamlines, the VN showed connectivity with the primary motor cortex (95.9%), primary somatosensory cortex (90.5%), premotor cortex (87.8%), hypothalamus (86.5%), posterior parietal cortex (75.7%), lateral prefrontal cortex (70.3%), ventromedial prefrontal cortex (51.4%), and orbitofrontal cortex (40.5%), respectively. These results suggest that the VN showed high connectivity with the cerebellum, thalamus, oculomotor nucleus, trochlear nucleus, abducens nucleus, and reticular formation, which are the brain regions related to the functions of the VN, including equilibrium, control of eye movements, conscious perception of movement, and spatial orientation. |
| first_indexed | 2024-04-14T06:54:38Z |
| format | Article |
| id | doaj.art-c43c13a91a0040e482f2812f322c2126 |
| institution | Directory Open Access Journal |
| issn | 1673-5374 |
| language | English |
| last_indexed | 2024-04-14T06:54:38Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Neural Regeneration Research |
| spelling | doaj.art-c43c13a91a0040e482f2812f322c21262022-12-22T02:06:56ZengWolters Kluwer Medknow PublicationsNeural Regeneration Research1673-53742018-01-0113472773010.4103/1673-5374.230304Structural neural connectivity of the vestibular nuclei in the human brain: a diffusion tensor imagingS studySung Ho JangMi Young LeeSang Seok YeoHyeok Gyu KwonMany animal studies have reported on the neural connectivity of the vestibular nuclei (VN). However, little is reported on the structural neural connectivity of the VN in the human brain. In this study, we attempted to investigate the structural neural connectivity of the VN in 37 healthy subjects using diffusion tensor tractography. A seed region of interest was placed on the isolated VN using probabilistic diffusion tensor tractography. Connectivity was defined as the incidence of connection between the VN and each brain region. The VN showed 100% connectivity with the cerebellum, thalamus, oculomotor nucleus, trochlear nucleus, abducens nucleus, and reticular formation, irrespective of thresholds. At the threshold of 5 streamlines, the VN showed connectivity with the primary motor cortex (95.9%), primary somatosensory cortex (90.5%), premotor cortex (87.8%), hypothalamus (86.5%), posterior parietal cortex (75.7%), lateral prefrontal cortex (70.3%), ventromedial prefrontal cortex (51.4%), and orbitofrontal cortex (40.5%), respectively. These results suggest that the VN showed high connectivity with the cerebellum, thalamus, oculomotor nucleus, trochlear nucleus, abducens nucleus, and reticular formation, which are the brain regions related to the functions of the VN, including equilibrium, control of eye movements, conscious perception of movement, and spatial orientation.http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=4;spage=727;epage=730;aulast=Jangnerve regeneration; vestibular nuclei; neural connectivity; diffusion tensor tractography; cerebellum; oculomotor nucleus; neural regeneration |
| spellingShingle | Sung Ho Jang Mi Young Lee Sang Seok Yeo Hyeok Gyu Kwon Structural neural connectivity of the vestibular nuclei in the human brain: a diffusion tensor imagingS study Neural Regeneration Research nerve regeneration; vestibular nuclei; neural connectivity; diffusion tensor tractography; cerebellum; oculomotor nucleus; neural regeneration |
| title | Structural neural connectivity of the vestibular nuclei in the human brain: a diffusion tensor imagingS study |
| title_full | Structural neural connectivity of the vestibular nuclei in the human brain: a diffusion tensor imagingS study |
| title_fullStr | Structural neural connectivity of the vestibular nuclei in the human brain: a diffusion tensor imagingS study |
| title_full_unstemmed | Structural neural connectivity of the vestibular nuclei in the human brain: a diffusion tensor imagingS study |
| title_short | Structural neural connectivity of the vestibular nuclei in the human brain: a diffusion tensor imagingS study |
| title_sort | structural neural connectivity of the vestibular nuclei in the human brain a diffusion tensor imagings study |
| topic | nerve regeneration; vestibular nuclei; neural connectivity; diffusion tensor tractography; cerebellum; oculomotor nucleus; neural regeneration |
| url | http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=4;spage=727;epage=730;aulast=Jang |
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