Comparison of skin prick allergy test in urban and rural children
Background Children who grow up in rural areas have a lower incidence of atopy and other allergic manifestations than children in urban areas. Several recent studies have suggested that agricultural exposure may protect children from developing asthma and atopy, but these findings are inconsistent....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Indonesian Pediatric Society Publishing House
2011-04-01
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| Series: | Paediatrica Indonesiana |
| Subjects: | |
| Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/892 |
| _version_ | 1818020175492939776 |
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| author | Fakhri Widyanto Rita Evalina Rusli Muhammad Ali Melda Deliana Lily Irsa M. Sjabaroeddin Loebis |
| author_facet | Fakhri Widyanto Rita Evalina Rusli Muhammad Ali Melda Deliana Lily Irsa M. Sjabaroeddin Loebis |
| author_sort | Fakhri Widyanto |
| collection | DOAJ |
| description | Background Children who grow up in rural areas have a lower incidence of atopy and other allergic manifestations than children in urban areas. Several recent studies have suggested that agricultural exposure may protect children from developing asthma and atopy, but these findings are inconsistent.
Objective To examine an association between living in rural or urban areas and skin prick allergy test results in children and to detennine associated risk factors for atopy.
Methods We conducted a cross-sectional study in Karo district (rural) and Medan (urban) in October-December 2009. We enrolled primary school children who had a history of atopy in their families. Skin prick testing was done on the volar side of the forearm and included eight aero-allergens: house dust mites, house dust, cotton, chicken feathers, cat dander, cockroaches, mould, and pollen. We analyzed the folloMng risk factors for
association Mth atopy: tobacco smoke, pets, livestock exposure, and having older sibling(s).
Results We recruited 49 children from the Karo district and 52 children from the city of Medan. There were significant associations between living in an urban area and positive skin prick test results for house dust mites and house dust compared to living in a rural area (P=0.04, 95% CI: 1.11 to 5.91; P=0.04, 95% CI: 1.13 to 12.45, respectively). The reverse was true for cockroach allergens (P=0.02, 95% CI: 0.16 to 0.81). Tobacco smoke and livestock exposure were associated Mth negative skin prick test results in rural children (P=O.03, 95% CI: 0.03 to 0.81 and P=0.002, 95% CI: 0.02 to 0.42, respectively). Multivariate analysis revealed that lack of livestock exposure was the major risk factor associated Mth any positive skin prick test results in rural children (P=0.004; 95% CI ; 0.02 to 0.49).
Conclusion There were differing associations between living in rural and urban areas to various skin prick test results in children. Lack of livestock exposure was the risk factor associated with positive skin prick test results in rural children. |
| first_indexed | 2024-04-14T08:02:26Z |
| format | Article |
| id | doaj.art-c43ed401ce024434befa726cc02e7ced |
| institution | Directory Open Access Journal |
| issn | 0030-9311 2338-476X |
| language | English |
| last_indexed | 2024-04-14T08:02:26Z |
| publishDate | 2011-04-01 |
| publisher | Indonesian Pediatric Society Publishing House |
| record_format | Article |
| series | Paediatrica Indonesiana |
| spelling | doaj.art-c43ed401ce024434befa726cc02e7ced2022-12-22T02:04:52ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2011-04-0151284810.14238/pi51.2.2011.84-8752Comparison of skin prick allergy test in urban and rural childrenFakhri Widyanto0Rita Evalina Rusli1Muhammad Ali2Melda Deliana3Lily Irsa4M. Sjabaroeddin Loebis5Department of Child Health, University Sumatera Utara Medical School/H. Adam Malik Hospital, Medan, North SumateraDepartment of Child Health, University Sumatera Utara Medical School/H. Adam Malik Hospital, Medan, North SumateraDepartment of Child Health, University Sumatera Utara Medical School/H. Adam Malik Hospital, Medan, North SumateraDepartment of Child Health, University Sumatera Utara Medical School/H. Adam Malik Hospital, Medan, North SumateraDepartment of Child Health, University Sumatera Utara Medical School/H. Adam Malik Hospital, Medan, North SumateraDepartment of Child Health, University Sumatera Utara Medical School/H. Adam Malik Hospital, Medan, North SumateraBackground Children who grow up in rural areas have a lower incidence of atopy and other allergic manifestations than children in urban areas. Several recent studies have suggested that agricultural exposure may protect children from developing asthma and atopy, but these findings are inconsistent. Objective To examine an association between living in rural or urban areas and skin prick allergy test results in children and to detennine associated risk factors for atopy. Methods We conducted a cross-sectional study in Karo district (rural) and Medan (urban) in October-December 2009. We enrolled primary school children who had a history of atopy in their families. Skin prick testing was done on the volar side of the forearm and included eight aero-allergens: house dust mites, house dust, cotton, chicken feathers, cat dander, cockroaches, mould, and pollen. We analyzed the folloMng risk factors for association Mth atopy: tobacco smoke, pets, livestock exposure, and having older sibling(s). Results We recruited 49 children from the Karo district and 52 children from the city of Medan. There were significant associations between living in an urban area and positive skin prick test results for house dust mites and house dust compared to living in a rural area (P=0.04, 95% CI: 1.11 to 5.91; P=0.04, 95% CI: 1.13 to 12.45, respectively). The reverse was true for cockroach allergens (P=0.02, 95% CI: 0.16 to 0.81). Tobacco smoke and livestock exposure were associated Mth negative skin prick test results in rural children (P=O.03, 95% CI: 0.03 to 0.81 and P=0.002, 95% CI: 0.02 to 0.42, respectively). Multivariate analysis revealed that lack of livestock exposure was the major risk factor associated Mth any positive skin prick test results in rural children (P=0.004; 95% CI ; 0.02 to 0.49). Conclusion There were differing associations between living in rural and urban areas to various skin prick test results in children. Lack of livestock exposure was the risk factor associated with positive skin prick test results in rural children.https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/892skin prick testchildrenruralurbanrisk factor |
| spellingShingle | Fakhri Widyanto Rita Evalina Rusli Muhammad Ali Melda Deliana Lily Irsa M. Sjabaroeddin Loebis Comparison of skin prick allergy test in urban and rural children Paediatrica Indonesiana skin prick test children rural urban risk factor |
| title | Comparison of skin prick allergy test in urban and rural children |
| title_full | Comparison of skin prick allergy test in urban and rural children |
| title_fullStr | Comparison of skin prick allergy test in urban and rural children |
| title_full_unstemmed | Comparison of skin prick allergy test in urban and rural children |
| title_short | Comparison of skin prick allergy test in urban and rural children |
| title_sort | comparison of skin prick allergy test in urban and rural children |
| topic | skin prick test children rural urban risk factor |
| url | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/892 |
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