THE INCIDENCE OF JUVENILE MYOCLONIC EPILEPSY AND ANALYSIS OF ITS THERAPY ACCORDING TO THE DATA OF THE “EPICENTER” (VOLGOGRAD)
Juvenile myoclonic epilepsy (JME) (Janz syndrome) is a form of idiopathic generalized epilepsy (IGE) of adolescence, which is characterized by massive bilateral myoclonic seizures occurring predominantly in the arms on awakening from sleep. A Proposed Diagnostic Scheme for People with Epileptic Seiz...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2015-06-01
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| Series: | Русский журнал детской неврологии |
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| Online Access: | https://rjdn.abvpress.ru/jour/article/view/52 |
| _version_ | 1797874497147109376 |
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| author | O. V. Belyaev E. A. Volkova |
| author_facet | O. V. Belyaev E. A. Volkova |
| author_sort | O. V. Belyaev |
| collection | DOAJ |
| description | Juvenile myoclonic epilepsy (JME) (Janz syndrome) is a form of idiopathic generalized epilepsy (IGE) of adolescence, which is characterized by massive bilateral myoclonic seizures occurring predominantly in the arms on awakening from sleep. A Proposed Diagnostic Scheme for People with Epileptic Seizures and with Epilepsy (2001) refers JME to a group of IGE with a variable phenotype. JME is one of the most com- mon forms of epilepsy (7 % among all forms of epilepsy and 27 % among its all idiopathic forms). The authors describe the history of epilepsy, the specific features of the course of the disease, its clinical manifestations, the characteristic types of seizures, and approaches to diagnosis and therapy. They also proposed the results of their investigation, the aim of study were epidemiological pattern of JME and the specific features of its therapy and remission in the Volgograd Region. The investigation showed that 83 % of the patents with JME in the Volgograd Region could achieve remission with medical treatment, as shown by the EpiCenter. Valproates are the drugs of choice (remission was achieved in 92 %). The most common combination was levetiracetam and valproate (71 % remission). Complete clinical and electroencephalographic remission of JME was achieved in 41 % of cases, valproates therewith remain to have benefits too (58 % remission). |
| first_indexed | 2024-04-10T01:31:58Z |
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| id | doaj.art-c441cc8136f14cf89556ade1fe9f508f |
| institution | Directory Open Access Journal |
| issn | 2073-8803 2412-9178 |
| language | Russian |
| last_indexed | 2024-04-10T01:31:58Z |
| publishDate | 2015-06-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Русский журнал детской неврологии |
| spelling | doaj.art-c441cc8136f14cf89556ade1fe9f508f2023-03-13T09:30:11ZrusABV-pressРусский журнал детской неврологии2073-88032412-91782015-06-01102131810.17650/2073-8803-2015-10-2-13-1846THE INCIDENCE OF JUVENILE MYOCLONIC EPILEPSY AND ANALYSIS OF ITS THERAPY ACCORDING TO THE DATA OF THE “EPICENTER” (VOLGOGRAD)O. V. Belyaev0E. A. Volkova1ООО «ЭпиЦентр»; Россия, 400131, Волгоград, ул. Донецкая, 14ООО «ЭпиЦентр»; Россия, 400131, Волгоград, ул. Донецкая, 14Juvenile myoclonic epilepsy (JME) (Janz syndrome) is a form of idiopathic generalized epilepsy (IGE) of adolescence, which is characterized by massive bilateral myoclonic seizures occurring predominantly in the arms on awakening from sleep. A Proposed Diagnostic Scheme for People with Epileptic Seizures and with Epilepsy (2001) refers JME to a group of IGE with a variable phenotype. JME is one of the most com- mon forms of epilepsy (7 % among all forms of epilepsy and 27 % among its all idiopathic forms). The authors describe the history of epilepsy, the specific features of the course of the disease, its clinical manifestations, the characteristic types of seizures, and approaches to diagnosis and therapy. They also proposed the results of their investigation, the aim of study were epidemiological pattern of JME and the specific features of its therapy and remission in the Volgograd Region. The investigation showed that 83 % of the patents with JME in the Volgograd Region could achieve remission with medical treatment, as shown by the EpiCenter. Valproates are the drugs of choice (remission was achieved in 92 %). The most common combination was levetiracetam and valproate (71 % remission). Complete clinical and electroencephalographic remission of JME was achieved in 41 % of cases, valproates therewith remain to have benefits too (58 % remission).https://rjdn.abvpress.ru/jour/article/view/52эпилепсияидиопатическая эпилепсияидиопатическая генерализованная эпилепсияюношеская миоклоническая эпилепсиясиндром янцаклиническая картинадиагностикалечениепрогнозремиссиявальпроатлеветирацетам |
| spellingShingle | O. V. Belyaev E. A. Volkova THE INCIDENCE OF JUVENILE MYOCLONIC EPILEPSY AND ANALYSIS OF ITS THERAPY ACCORDING TO THE DATA OF THE “EPICENTER” (VOLGOGRAD) Русский журнал детской неврологии эпилепсия идиопатическая эпилепсия идиопатическая генерализованная эпилепсия юношеская миоклоническая эпилепсия синдром янца клиническая картина диагностика лечение прогноз ремиссия вальпроат леветирацетам |
| title | THE INCIDENCE OF JUVENILE MYOCLONIC EPILEPSY AND ANALYSIS OF ITS THERAPY ACCORDING TO THE DATA OF THE “EPICENTER” (VOLGOGRAD) |
| title_full | THE INCIDENCE OF JUVENILE MYOCLONIC EPILEPSY AND ANALYSIS OF ITS THERAPY ACCORDING TO THE DATA OF THE “EPICENTER” (VOLGOGRAD) |
| title_fullStr | THE INCIDENCE OF JUVENILE MYOCLONIC EPILEPSY AND ANALYSIS OF ITS THERAPY ACCORDING TO THE DATA OF THE “EPICENTER” (VOLGOGRAD) |
| title_full_unstemmed | THE INCIDENCE OF JUVENILE MYOCLONIC EPILEPSY AND ANALYSIS OF ITS THERAPY ACCORDING TO THE DATA OF THE “EPICENTER” (VOLGOGRAD) |
| title_short | THE INCIDENCE OF JUVENILE MYOCLONIC EPILEPSY AND ANALYSIS OF ITS THERAPY ACCORDING TO THE DATA OF THE “EPICENTER” (VOLGOGRAD) |
| title_sort | incidence of juvenile myoclonic epilepsy and analysis of its therapy according to the data of the epicenter volgograd |
| topic | эпилепсия идиопатическая эпилепсия идиопатическая генерализованная эпилепсия юношеская миоклоническая эпилепсия синдром янца клиническая картина диагностика лечение прогноз ремиссия вальпроат леветирацетам |
| url | https://rjdn.abvpress.ru/jour/article/view/52 |
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