Assessment of hypoxemia among young adults with sickle cell anaemia in steady state in southwestern Nigeria: a crosssectional study
Abstract Objectives Hypoxia is a known feature of sickle cell anaemia (SCA) which results from chronic anaemia and recurrent vaso-occlusive crisis (VOC) which can cause tissue ischaemia that leads to an end organ damage. The hallmark of SCA is chronic anaemia and recurrent vaso-occlusive crisis. The...
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| Format: | Article |
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BMC
2024-04-01
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| Series: | BMC Research Notes |
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| Online Access: | https://doi.org/10.1186/s13104-024-06765-0 |
| _version_ | 1797209582251016192 |
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| author | Asafa M. A. Ahmed I. O Afolabi M. S. Bolarinwa R. A. Ogunlade O. |
| author_facet | Asafa M. A. Ahmed I. O Afolabi M. S. Bolarinwa R. A. Ogunlade O. |
| author_sort | Asafa M. A. |
| collection | DOAJ |
| description | Abstract Objectives Hypoxia is a known feature of sickle cell anaemia (SCA) which results from chronic anaemia and recurrent vaso-occlusive crisis (VOC) which can cause tissue ischaemia that leads to an end organ damage. The hallmark of SCA is chronic anaemia and recurrent vaso-occlusive crisis. The aim of this study is to compare the oxygen saturation of sickle cell anaemic individuals with the normal haemoglobin type (Hb AA) control and also to determine the prevalence of hypoxemia among SCA. Results Two-hundred and twenty-two (136 Hb SS and 86 Hb AA) participated in the study. The mean ± SD of age (years), oxygen saturation (%) and pulse rate (bpm) of participants with sickle cell anaemia and Hb AA control were 21.85 ± 3.04 and 22.14 ± 3.18 (t = 0.701, p = 0.436), 95.21 ± 3.02 and 98.07 ± 0.81 (t=-8.598, p < 0.0001) and 77.10 ± 9.28 and 73.16 ± 8.52 (t = 3.173, p = 0.002) respectively. The prevalence of hypoxemia among SCA participants was 47.1%. Prevalence of hypoxemia in males with SCA was 60.9% while 39.1% of the females had hypoxemia. |
| first_indexed | 2024-04-24T09:56:59Z |
| format | Article |
| id | doaj.art-c444992684c744bd8548d67df7e40a25 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-04-24T09:56:59Z |
| publishDate | 2024-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-c444992684c744bd8548d67df7e40a252024-04-14T11:07:02ZengBMCBMC Research Notes1756-05002024-04-011711410.1186/s13104-024-06765-0Assessment of hypoxemia among young adults with sickle cell anaemia in steady state in southwestern Nigeria: a crosssectional studyAsafa M. A.0Ahmed I. O1Afolabi M. S.2Bolarinwa R. A.3Ogunlade O.4Department of Physiological Sciences, Faculty of Basic Medical Sciences, College of Health Sciences, Obafemi Awolowo UniversityDepartment of Haematology and Blood Transfusion, Obafemi Awolowo University Teaching Hospital ComplexRespiratory Unit, Department of Internal Medicine, Obafemi Awolowo University Teaching Hospital ComplexDepartment of Haematology and Blood Transfusion, Obafemi Awolowo University Teaching Hospital ComplexDepartment of Physiological Sciences, Faculty of Basic Medical Sciences, College of Health Sciences, Obafemi Awolowo UniversityAbstract Objectives Hypoxia is a known feature of sickle cell anaemia (SCA) which results from chronic anaemia and recurrent vaso-occlusive crisis (VOC) which can cause tissue ischaemia that leads to an end organ damage. The hallmark of SCA is chronic anaemia and recurrent vaso-occlusive crisis. The aim of this study is to compare the oxygen saturation of sickle cell anaemic individuals with the normal haemoglobin type (Hb AA) control and also to determine the prevalence of hypoxemia among SCA. Results Two-hundred and twenty-two (136 Hb SS and 86 Hb AA) participated in the study. The mean ± SD of age (years), oxygen saturation (%) and pulse rate (bpm) of participants with sickle cell anaemia and Hb AA control were 21.85 ± 3.04 and 22.14 ± 3.18 (t = 0.701, p = 0.436), 95.21 ± 3.02 and 98.07 ± 0.81 (t=-8.598, p < 0.0001) and 77.10 ± 9.28 and 73.16 ± 8.52 (t = 3.173, p = 0.002) respectively. The prevalence of hypoxemia among SCA participants was 47.1%. Prevalence of hypoxemia in males with SCA was 60.9% while 39.1% of the females had hypoxemia.https://doi.org/10.1186/s13104-024-06765-0HypoxemiaSickle cell anaemiaSteady stateVaso-occlusive crisis |
| spellingShingle | Asafa M. A. Ahmed I. O Afolabi M. S. Bolarinwa R. A. Ogunlade O. Assessment of hypoxemia among young adults with sickle cell anaemia in steady state in southwestern Nigeria: a crosssectional study BMC Research Notes Hypoxemia Sickle cell anaemia Steady state Vaso-occlusive crisis |
| title | Assessment of hypoxemia among young adults with sickle cell anaemia in steady state in southwestern Nigeria: a crosssectional study |
| title_full | Assessment of hypoxemia among young adults with sickle cell anaemia in steady state in southwestern Nigeria: a crosssectional study |
| title_fullStr | Assessment of hypoxemia among young adults with sickle cell anaemia in steady state in southwestern Nigeria: a crosssectional study |
| title_full_unstemmed | Assessment of hypoxemia among young adults with sickle cell anaemia in steady state in southwestern Nigeria: a crosssectional study |
| title_short | Assessment of hypoxemia among young adults with sickle cell anaemia in steady state in southwestern Nigeria: a crosssectional study |
| title_sort | assessment of hypoxemia among young adults with sickle cell anaemia in steady state in southwestern nigeria a crosssectional study |
| topic | Hypoxemia Sickle cell anaemia Steady state Vaso-occlusive crisis |
| url | https://doi.org/10.1186/s13104-024-06765-0 |
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