Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome

Parkinson's disease (PD) is a common neurodegenerative disorder. Some patients with advanced-stage disease are accompanied by emergencies and critical issues such as dyskinesia-hyperpyrexia syndrome (DHS), parkinsonism-hyperpyrexia syndrome (PHS), and serotonin syndrome (SS). In this study, we...

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Main Authors: Bohan Luo, Hainan Zhang, Lixia Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1234974/full
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author Bohan Luo
Hainan Zhang
Lixia Qin
author_facet Bohan Luo
Hainan Zhang
Lixia Qin
author_sort Bohan Luo
collection DOAJ
description Parkinson's disease (PD) is a common neurodegenerative disorder. Some patients with advanced-stage disease are accompanied by emergencies and critical issues such as dyskinesia-hyperpyrexia syndrome (DHS), parkinsonism-hyperpyrexia syndrome (PHS), and serotonin syndrome (SS). In this study, we report a patient with reversible encephalopathy caused by DHS who presented with an acute onset of fidgetiness, dyskinesia, and hyperpyrexia after antiparkinsonian drug abuse. In the present case, brain magnetic resonance imaging (MRI) showed multiple abnormal signals in the cortex and subcortex of the bilateral parietal and occipital lobes that resolved within weeks, which coincided with the characteristic MRI findings in posterior reversible encephalopathy (PRES). Our report expands on the neuroimaging features of DHS and highlights the importance of early identification, diagnosis, and treatment to improve patient prognosis.
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spelling doaj.art-c444a50af28e41d7ab80ddd8417af83b2023-08-15T03:26:11ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-08-011410.3389/fneur.2023.12349741234974Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndromeBohan LuoHainan ZhangLixia QinParkinson's disease (PD) is a common neurodegenerative disorder. Some patients with advanced-stage disease are accompanied by emergencies and critical issues such as dyskinesia-hyperpyrexia syndrome (DHS), parkinsonism-hyperpyrexia syndrome (PHS), and serotonin syndrome (SS). In this study, we report a patient with reversible encephalopathy caused by DHS who presented with an acute onset of fidgetiness, dyskinesia, and hyperpyrexia after antiparkinsonian drug abuse. In the present case, brain magnetic resonance imaging (MRI) showed multiple abnormal signals in the cortex and subcortex of the bilateral parietal and occipital lobes that resolved within weeks, which coincided with the characteristic MRI findings in posterior reversible encephalopathy (PRES). Our report expands on the neuroimaging features of DHS and highlights the importance of early identification, diagnosis, and treatment to improve patient prognosis.https://www.frontiersin.org/articles/10.3389/fneur.2023.1234974/fullreversible encephalopathyParkinson's diseasedyskinesia-hyperpyrexia syndromeemergencyMRI findings
spellingShingle Bohan Luo
Hainan Zhang
Lixia Qin
Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
Frontiers in Neurology
reversible encephalopathy
Parkinson's disease
dyskinesia-hyperpyrexia syndrome
emergency
MRI findings
title Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_full Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_fullStr Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_full_unstemmed Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_short Case report: Reversible encephalopathy caused by dyskinesia-hyperpyrexia syndrome
title_sort case report reversible encephalopathy caused by dyskinesia hyperpyrexia syndrome
topic reversible encephalopathy
Parkinson's disease
dyskinesia-hyperpyrexia syndrome
emergency
MRI findings
url https://www.frontiersin.org/articles/10.3389/fneur.2023.1234974/full
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