Elimination of onchocerciasis in Africa by 2025: the need for a broad perspective
Abstract Background In response to the recent publication “Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes” by Dadzie et al., it is important to clarify and highlight the positive and unequivocal research and operati...
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| Format: | Article |
| Language: | English |
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BMC
2019-07-01
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| Series: | Infectious Diseases of Poverty |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40249-019-0557-1 |
| _version_ | 1818303134346248192 |
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| author | Ed Cupp Mauricio Sauerbrey Vitaliano Cama Mark Eberhard Patrick J. Lammie Thomas R. Unnasch |
| author_facet | Ed Cupp Mauricio Sauerbrey Vitaliano Cama Mark Eberhard Patrick J. Lammie Thomas R. Unnasch |
| author_sort | Ed Cupp |
| collection | DOAJ |
| description | Abstract Background In response to the recent publication “Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes” by Dadzie et al., it is important to clarify and highlight the positive and unequivocal research and operational contributions from the American experience towards the worldwide elimination of human onchocerciasis (river blindness). Main text The strategies of twice or more rounds of mass drug administration (MDA) of ivermectin per year, as well as the use of OV-16 serology have allowed four American countries to be verified by World Health Organization to have eliminated transmission of Onchocerca volvulus, the etiological agent. These advances were also implemented in Sudan and Uganda; currently, both are the only African countries where ivermectin MDA was safely stopped in several transmission zones. Conclusions Programmatic treatment and evaluation approaches, pioneered in the Americas, are the most efficient among the existing tools for elimination, and their broader use could catalyze the successful elimination of this disease in Africa. |
| first_indexed | 2024-12-13T05:49:58Z |
| format | Article |
| id | doaj.art-c448edb5df0e41cca39968e0eccd3134 |
| institution | Directory Open Access Journal |
| issn | 2049-9957 |
| language | English |
| last_indexed | 2024-12-13T05:49:58Z |
| publishDate | 2019-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Infectious Diseases of Poverty |
| spelling | doaj.art-c448edb5df0e41cca39968e0eccd31342022-12-21T23:57:34ZengBMCInfectious Diseases of Poverty2049-99572019-07-01811510.1186/s40249-019-0557-1Elimination of onchocerciasis in Africa by 2025: the need for a broad perspectiveEd Cupp0Mauricio Sauerbrey1Vitaliano Cama2Mark Eberhard3Patrick J. Lammie4Thomas R. Unnasch5Department of Entomology and Plant Pathology, Auburn UniversityOnchocerciasis Elimination Program for the AmericasCenters for Disease Control and PreventionCenters for Disease Control and PreventionTask Force for Global HealthCenter for Global Health Infectious Diseases, University of South Florida College of Public HealthAbstract Background In response to the recent publication “Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes” by Dadzie et al., it is important to clarify and highlight the positive and unequivocal research and operational contributions from the American experience towards the worldwide elimination of human onchocerciasis (river blindness). Main text The strategies of twice or more rounds of mass drug administration (MDA) of ivermectin per year, as well as the use of OV-16 serology have allowed four American countries to be verified by World Health Organization to have eliminated transmission of Onchocerca volvulus, the etiological agent. These advances were also implemented in Sudan and Uganda; currently, both are the only African countries where ivermectin MDA was safely stopped in several transmission zones. Conclusions Programmatic treatment and evaluation approaches, pioneered in the Americas, are the most efficient among the existing tools for elimination, and their broader use could catalyze the successful elimination of this disease in Africa.http://link.springer.com/article/10.1186/s40249-019-0557-1OnchocerciasisIvermectinOnchocerciasis in the AmericasElimination, African Programme for onchocerciasis controlOnchocerciasis control program of West Africa |
| spellingShingle | Ed Cupp Mauricio Sauerbrey Vitaliano Cama Mark Eberhard Patrick J. Lammie Thomas R. Unnasch Elimination of onchocerciasis in Africa by 2025: the need for a broad perspective Infectious Diseases of Poverty Onchocerciasis Ivermectin Onchocerciasis in the Americas Elimination, African Programme for onchocerciasis control Onchocerciasis control program of West Africa |
| title | Elimination of onchocerciasis in Africa by 2025: the need for a broad perspective |
| title_full | Elimination of onchocerciasis in Africa by 2025: the need for a broad perspective |
| title_fullStr | Elimination of onchocerciasis in Africa by 2025: the need for a broad perspective |
| title_full_unstemmed | Elimination of onchocerciasis in Africa by 2025: the need for a broad perspective |
| title_short | Elimination of onchocerciasis in Africa by 2025: the need for a broad perspective |
| title_sort | elimination of onchocerciasis in africa by 2025 the need for a broad perspective |
| topic | Onchocerciasis Ivermectin Onchocerciasis in the Americas Elimination, African Programme for onchocerciasis control Onchocerciasis control program of West Africa |
| url | http://link.springer.com/article/10.1186/s40249-019-0557-1 |
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