Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis

Introduction: Neopterin and 7,8-dihydroneopterin are used as biomarkers of oxidative stress and inflammation, but the effect of kidney function on these measurements has not been extensively explored. We examine the levels of oxidative stress, inflammation and kidney function in intensive patients a...

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Main Authors: Baxter-Parker Gregory, Gaddam Ravinder Reddy, Moltchanova Elena, Carr Anitra, Shaw Geoff, Chambers Stephen, Gieseg Steven P.
Format: Article
Language:English
Published: De Gruyter 2020-05-01
Series:Pteridines
Subjects:
Online Access:https://doi.org/10.1515/pteridines-2020-0015
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author Baxter-Parker Gregory
Gaddam Ravinder Reddy
Moltchanova Elena
Carr Anitra
Shaw Geoff
Chambers Stephen
Gieseg Steven P.
author_facet Baxter-Parker Gregory
Gaddam Ravinder Reddy
Moltchanova Elena
Carr Anitra
Shaw Geoff
Chambers Stephen
Gieseg Steven P.
author_sort Baxter-Parker Gregory
collection DOAJ
description Introduction: Neopterin and 7,8-dihydroneopterin are used as biomarkers of oxidative stress and inflammation, but the effect of kidney function on these measurements has not been extensively explored. We examine the levels of oxidative stress, inflammation and kidney function in intensive patients and compare them to equivalent patients without sepsis.
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spelling doaj.art-c4498e7c1c92498d979a94775807b43c2022-12-22T04:36:03ZengDe GruyterPteridines0933-48072195-47202020-05-01311688210.1515/pteridines-2020-0015pteridines-2020-0015Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysisBaxter-Parker Gregory0Gaddam Ravinder Reddy1Moltchanova Elena2Carr Anitra3Shaw Geoff4Chambers Stephen5Gieseg Steven P.6School of Biological Sciences, University of Canterbury, Christchurch, New ZealandDivision of Cardiovascular Medicine, Department of Internal Medicine, Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USADepartment of Mathematics and Statistics, University of Canterbury, Christchurch, New ZealandDepartment of Pathology & Biomedical Science, University of Otago Christchurch, Christchurch, New ZealandDepartment of Intensive Care, Christchurch Hospital, New Zealand Department of Pathology & Biomedical Science, University of Otago Christchurch, Christchurch, New ZealandSchool of Biological Sciences, University of Canterbury, Christchurch, New ZealandIntroduction: Neopterin and 7,8-dihydroneopterin are used as biomarkers of oxidative stress and inflammation, but the effect of kidney function on these measurements has not been extensively explored. We examine the levels of oxidative stress, inflammation and kidney function in intensive patients and compare them to equivalent patients without sepsis.https://doi.org/10.1515/pteridines-2020-0015sepsisneopterin7,8-dihydroneopterinkidney functioninflammationbiomarkers
spellingShingle Baxter-Parker Gregory
Gaddam Ravinder Reddy
Moltchanova Elena
Carr Anitra
Shaw Geoff
Chambers Stephen
Gieseg Steven P.
Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis
Pteridines
sepsis
neopterin
7,8-dihydroneopterin
kidney function
inflammation
biomarkers
title Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis
title_full Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis
title_fullStr Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis
title_full_unstemmed Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis
title_short Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis
title_sort oxidative stress and immune cell activation quantification in sepsis and non sepsis critical care patients by neopterin 7 8 dihydroneopterin analysis
topic sepsis
neopterin
7,8-dihydroneopterin
kidney function
inflammation
biomarkers
url https://doi.org/10.1515/pteridines-2020-0015
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