A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19

Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on “Meet the Press” that “[T]he U.S. needs a ‘breakthrough’ in coronavirus testing to help screen Americans and get a more accurate picture of the virus’ spread.” We have been involved with biopathogen detection sinc...

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Main Authors: Rajil Navid, Sokolov Alexei, Yi Zhenhuan, Adams Garry, Agarwal Girish, Belousov Vsevolod, Brick Robert, Chapin Kimberly, Cirillo Jeffrey, Deckert Volker, Delfan Sahar, Esmaeili Shahriar, Fernández-González Alma, Fry Edward, Han Zehua, Hemmer Philip, Kattawar George, Kim Moochan, Lee Ming-Che, Lu Chao-Yang, Mogford Jon, Neuman Benjamin, Pan Jian-Wei, Peng Tao, Poor Vincent, Scully Steven, Shih Yanhua, Suckewer Szymon, Svidzinsky Anatoly, Verhoef Aart, Wang Dawei, Wang Kai, Yang Lan, Zheltikov Aleksei, Zhu Shiyao, Zubairy Suhail, Scully Marlan
Format: Article
Language:English
Published: De Gruyter 2020-09-01
Series:Nanophotonics
Subjects:
Online Access:https://doi.org/10.1515/nanoph-2020-0357
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author Rajil Navid
Sokolov Alexei
Yi Zhenhuan
Adams Garry
Agarwal Girish
Belousov Vsevolod
Brick Robert
Chapin Kimberly
Cirillo Jeffrey
Deckert Volker
Delfan Sahar
Esmaeili Shahriar
Fernández-González Alma
Fry Edward
Han Zehua
Hemmer Philip
Kattawar George
Kim Moochan
Lee Ming-Che
Lu Chao-Yang
Mogford Jon
Neuman Benjamin
Pan Jian-Wei
Peng Tao
Poor Vincent
Scully Steven
Shih Yanhua
Suckewer Szymon
Svidzinsky Anatoly
Verhoef Aart
Wang Dawei
Wang Kai
Yang Lan
Zheltikov Aleksei
Zhu Shiyao
Zubairy Suhail
Scully Marlan
author_facet Rajil Navid
Sokolov Alexei
Yi Zhenhuan
Adams Garry
Agarwal Girish
Belousov Vsevolod
Brick Robert
Chapin Kimberly
Cirillo Jeffrey
Deckert Volker
Delfan Sahar
Esmaeili Shahriar
Fernández-González Alma
Fry Edward
Han Zehua
Hemmer Philip
Kattawar George
Kim Moochan
Lee Ming-Che
Lu Chao-Yang
Mogford Jon
Neuman Benjamin
Pan Jian-Wei
Peng Tao
Poor Vincent
Scully Steven
Shih Yanhua
Suckewer Szymon
Svidzinsky Anatoly
Verhoef Aart
Wang Dawei
Wang Kai
Yang Lan
Zheltikov Aleksei
Zhu Shiyao
Zubairy Suhail
Scully Marlan
author_sort Rajil Navid
collection DOAJ
description Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on “Meet the Press” that “[T]he U.S. needs a ‘breakthrough’ in coronavirus testing to help screen Americans and get a more accurate picture of the virus’ spread.” We have been involved with biopathogen detection since the 2001 anthrax attacks and were the first to detect anthrax in real-time. A variation on the laser spectroscopic techniques we developed for the rapid detection of anthrax can be applied to detect the Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2 virus). In addition to detecting a single virus, this technique allows us to read its surface protein structure. In particular, we have been conducting research based on a variety of quantum optical approaches aimed at improving our ability to detect Corona Virus Disease-2019 (COVID-19) viral infection. Indeed, the detection of a small concentration of antibodies, after an infection has passed, is a challenging problem. Likewise, the early detection of disease, even before a detectible antibody population has been established, is very important. Our team is researching both aspects of this problem. The paper is written to stimulate the interest of both physical and biological scientists in this important problem. It is thus written as a combination of tutorial (review) and future work (preview). We join Prof. Federico Capasso and Editor Dennis Couwenberg in expressing our appreciation to all those working so heroically on all aspects of the COVID-19 problem. And we thank Drs. Capasso and Couwenberg for their invitation to write this paper.
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spelling doaj.art-c44a5c98cd3f497db365184d2d1b71332022-12-21T23:30:41ZengDe GruyterNanophotonics2192-86062192-86142020-09-0110123524610.1515/nanoph-2020-0357A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19Rajil Navid0Sokolov Alexei1Yi Zhenhuan2Adams Garry3Agarwal Girish4Belousov Vsevolod5Brick Robert6Chapin Kimberly7Cirillo Jeffrey8Deckert Volker9Delfan Sahar10Esmaeili Shahriar11Fernández-González Alma12Fry Edward13Han Zehua14Hemmer Philip15Kattawar George16Kim Moochan17Lee Ming-Che18Lu Chao-Yang19Mogford Jon20Neuman Benjamin21Pan Jian-Wei22Peng Tao23Poor Vincent24Scully Steven25Shih Yanhua26Suckewer Szymon27Svidzinsky Anatoly28Verhoef Aart29Wang Dawei30Wang Kai31Yang Lan32Zheltikov Aleksei33Zhu Shiyao34Zubairy Suhail35Scully Marlan36Texas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USAShemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow117997, RussiaTexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USAUniversity of Science and Technology of China, Hefei, Anhui, 230026, P. R. ChinaTexas A&M University System, College Station, TX77840, USATexas A&M University, College Station, TX77843, USAUniversity of Science and Technology of China, Hefei, Anhui, 230026, P. R. ChinaTexas A&M University, College Station, TX77843, USAPrinceton University, Princeton, NJ08544, USACollins Aerospace, Richardson, TX75082, USAUniversity of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD21250, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USAZhejiang University, 38 Zheda Rd, Hangzhou, 310027, P. R. ChinaTexas A&M University, College Station, TX77843, USAWashington University, St. Louis, MO63130, USATexas A&M University, College Station, TX77843, USAZhejiang University, 38 Zheda Rd, Hangzhou, 310027, P. R. ChinaTexas A&M University, College Station, TX77843, USATexas A&M University, College Station, TX77843, USADr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on “Meet the Press” that “[T]he U.S. needs a ‘breakthrough’ in coronavirus testing to help screen Americans and get a more accurate picture of the virus’ spread.” We have been involved with biopathogen detection since the 2001 anthrax attacks and were the first to detect anthrax in real-time. A variation on the laser spectroscopic techniques we developed for the rapid detection of anthrax can be applied to detect the Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2 virus). In addition to detecting a single virus, this technique allows us to read its surface protein structure. In particular, we have been conducting research based on a variety of quantum optical approaches aimed at improving our ability to detect Corona Virus Disease-2019 (COVID-19) viral infection. Indeed, the detection of a small concentration of antibodies, after an infection has passed, is a challenging problem. Likewise, the early detection of disease, even before a detectible antibody population has been established, is very important. Our team is researching both aspects of this problem. The paper is written to stimulate the interest of both physical and biological scientists in this important problem. It is thus written as a combination of tutorial (review) and future work (preview). We join Prof. Federico Capasso and Editor Dennis Couwenberg in expressing our appreciation to all those working so heroically on all aspects of the COVID-19 problem. And we thank Drs. Capasso and Couwenberg for their invitation to write this paper.https://doi.org/10.1515/nanoph-2020-0357detection of sar-cov-2 virushollow-core fiberslaser spectroscopic techniquenanophotonics
spellingShingle Rajil Navid
Sokolov Alexei
Yi Zhenhuan
Adams Garry
Agarwal Girish
Belousov Vsevolod
Brick Robert
Chapin Kimberly
Cirillo Jeffrey
Deckert Volker
Delfan Sahar
Esmaeili Shahriar
Fernández-González Alma
Fry Edward
Han Zehua
Hemmer Philip
Kattawar George
Kim Moochan
Lee Ming-Che
Lu Chao-Yang
Mogford Jon
Neuman Benjamin
Pan Jian-Wei
Peng Tao
Poor Vincent
Scully Steven
Shih Yanhua
Suckewer Szymon
Svidzinsky Anatoly
Verhoef Aart
Wang Dawei
Wang Kai
Yang Lan
Zheltikov Aleksei
Zhu Shiyao
Zubairy Suhail
Scully Marlan
A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19
Nanophotonics
detection of sar-cov-2 virus
hollow-core fibers
laser spectroscopic technique
nanophotonics
title A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19
title_full A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19
title_fullStr A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19
title_full_unstemmed A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19
title_short A fiber optic–nanophotonic approach to the detection of antibodies and viral particles of COVID-19
title_sort fiber optic nanophotonic approach to the detection of antibodies and viral particles of covid 19
topic detection of sar-cov-2 virus
hollow-core fibers
laser spectroscopic technique
nanophotonics
url https://doi.org/10.1515/nanoph-2020-0357
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